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Hydroquinidine

Name: Hydroquinidine
Brand: TargetMol
SKU: T1334
Rating: 4.5 (1 reviews)

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Catalog No. T1334Cas No. 1435-55-8

Alias Hydroconquinine, Hydroconchinine, Dihydroquinine, Dihydroquinidine, (+)-Hydroquinidine

Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.

Hydroquinidine

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Purity: 99.68%

Catalog No. T1334Alias Hydroconquinine, Hydroconchinine, Dihydroquinine, Dihydroquinidine, (+)-HydroquinidineCas No. 1435-55-8

Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$29	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.68%

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Hydroquinidine AI Summary

Hydroquinidine has been evaluated for its antiviral activity against SARS-CoV-2. Assays performed involved the measurement of inhibition of SARS-CoV-2-induced cytotoxicity in VERO-6 cells at a concentration of 10 µM, with a 48-hour exposure to the virus. The findings revealed an IC50 value greater than 20,000 nM, specifically 19,952.62 nM, indicating a moderate to low potency in preventing virus-induced cytotoxicity..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.
Synonyms	Hydroconquinine, Hydroconchinine, Dihydroquinine, Dihydroquinidine, (+)-Hydroquinidine

Chemical Properties

Molecular Weight	326.43
Formula	C₂₀H₂₆N₂O₂
Cas No.	1435-55-8
Smiles	[H][C@@]12CCN(C[C@@H]1CC)[C@]([H])(C2)[C@@H](O)c1ccnc2ccc(OC)cc12
Relative Density.	1.1117 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (183.81 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.13 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0634 mL	15.3172 mL	30.6344 mL	153.1722 mL
5 mM	0.6127 mL	3.0634 mL	6.1269 mL	30.6344 mL
10 mM	0.3063 mL	1.5317 mL	3.0634 mL	15.3172 mL
20 mM	0.1532 mL	0.7659 mL	1.5317 mL	7.6586 mL
50 mM	0.0613 mL	0.3063 mL	0.6127 mL	3.0634 mL
100 mM	0.0306 mL	0.1532 mL	0.3063 mL	1.5317 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc