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Sulfo-NHS-Acetate

Name: Sulfo-NHS-Acetate
Brand: TargetMol
SKU: T16959
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T16959Cas No. 152305-87-8

Alias Sulfosuccinimidyl acetate

Sulfo-NHS-Acetate (Sulfosuccinimidyl acetate) is a PROTAC linker belonging to the alkyl chain class, useful for synthesizing PROTAC molecules.

Sulfo-NHS-Acetate

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Purity: 98.33%

Catalog No. T16959Alias Sulfosuccinimidyl acetateCas No. 152305-87-8

Sulfo-NHS-Acetate (Sulfosuccinimidyl acetate) is a PROTAC linker belonging to the alkyl chain class, useful for synthesizing PROTAC molecules.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	$35	In Stock	In Stock
25 mg	$54	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.33%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Sulfo-NHS-Acetate (Sulfosuccinimidyl acetate) is a PROTAC linker belonging to the alkyl chain class, useful for synthesizing PROTAC molecules.
In vitro	PROTACs (Proteolysis-Targeting Chimeras) consist of two ligands joined by a linker: one binding an E3 ubiquitin ligase and the other targeting the specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Synonyms	Sulfosuccinimidyl acetate

Chemical Properties

Molecular Weight	237.19
Formula	C₆H₇NO₇S
Cas No.	152305-87-8
Smiles	O=C(ON1C(=O)CC(C1=O)S(=O)(=O)O)C
Relative Density.	1.80 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (421.6 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2160 mL	21.0801 mL	42.1603 mL	210.8015 mL
5 mM	0.8432 mL	4.2160 mL	8.4321 mL	42.1603 mL
10 mM	0.4216 mL	2.1080 mL	4.2160 mL	21.0801 mL
20 mM	0.2108 mL	1.0540 mL	2.1080 mL	10.5401 mL
50 mM	0.0843 mL	0.4216 mL	0.8432 mL	4.2160 mL
100 mM	0.0422 mL	0.2108 mL	0.4216 mL	2.1080 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc