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BMS-394136

Name: BMS-394136
Brand: TargetMol
SKU: T30520
Price: 260 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T30520Cas No. 343246-73-1

Alias BMS394136;UNII-M694U7167K, BMS394136, BMS 394136

BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.

BMS-394136

🥰Excellent

Purity: 98.67%

Catalog No. T30520Alias BMS394136;UNII-M694U7167K, BMS394136, BMS 394136Cas No. 343246-73-1

BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.

Pack Size	Price	Availability
1 mg	$260	In Stock
5 mg	$646	In Stock
10 mg	$919	In Stock
25 mg	$1,380	In Stock
50 mg	$1,860	In Stock
100 mg	$2,490	In Stock
500 mg	$4,930	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.67%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
Synonyms	BMS394136;UNII-M694U7167K, BMS394136, BMS 394136

Chemical Properties

Molecular Weight	471.35
Formula	C₂₄H₂₁Cl₂FN₄O
Cas No.	343246-73-1
Smiles	C(=O)(C=1[C@H](N2C(NC1C)=CC=N2)C3=CC(Cl)=C(Cl)C=C3)N4[C@@H](CCC4)C5=CC=C(F)C=C5
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (106.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1216 mL	10.6078 mL	21.2157 mL	106.0783 mL
5 mM	0.4243 mL	2.1216 mL	4.2431 mL	21.2157 mL
10 mM	0.2122 mL	1.0608 mL	2.1216 mL	10.6078 mL
20 mM	0.1061 mL	0.5304 mL	1.0608 mL	5.3039 mL
50 mM	0.0424 mL	0.2122 mL	0.4243 mL	2.1216 mL
100 mM	0.0212 mL	0.1061 mL	0.2122 mL	1.0608 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc