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BMS-394136

Name: BMS-394136
Brand: TargetMol
SKU: T30520
Price: 260 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T30520Cas No. 343246-73-1

Alias BMS394136;UNII-M694U7167K, BMS394136, BMS 394136

BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.

BMS-394136

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Purity: 99.95%

Catalog No. T30520Alias BMS394136;UNII-M694U7167K, BMS394136, BMS 394136Cas No. 343246-73-1

BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$260	In Stock	In Stock
5 mg	$646	In Stock	In Stock
10 mg	$919	In Stock	In Stock
25 mg	$1,380	In Stock	In Stock
50 mg	$1,860	In Stock	In Stock
100 mg	$2,490	In Stock	In Stock
500 mg	$4,930	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.95%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
Synonyms	BMS394136;UNII-M694U7167K, BMS394136, BMS 394136

Chemical Properties

Molecular Weight	471.35
Formula	C₂₄H₂₁Cl₂FN₄O
Cas No.	343246-73-1
Smiles	C(=O)(C=1[C@H](N2C(NC1C)=CC=N2)C3=CC(Cl)=C(Cl)C=C3)N4[C@@H](CCC4)C5=CC=C(F)C=C5
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (106.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1216 mL	10.6078 mL	21.2157 mL	106.0783 mL
5 mM	0.4243 mL	2.1216 mL	4.2431 mL	21.2157 mL
10 mM	0.2122 mL	1.0608 mL	2.1216 mL	10.6078 mL
20 mM	0.1061 mL	0.5304 mL	1.0608 mL	5.3039 mL
50 mM	0.0424 mL	0.2122 mL	0.4243 mL	2.1216 mL
100 mM	0.0212 mL	0.1061 mL	0.2122 mL	1.0608 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc