4-(ethoxycarbonyl)-1-cyclohexanone

4-(Ethoxycarbonyl)-1-cyclohexanone is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

4-(1-Phenylethyl)resorcinol (4-(1-Phenylethyl)benzene-1,3-diol) is a skin brightening agent that is a cosmetic additive. It works by inhibiting melanin production, reducing the appearance of dark spots, hyperpigmentation and uneven skin tone, and brightening the skin tone to reduce dullness.4-(1-Phenylethyl)resorcinol is generally regarded as safe in the cosmetic industry, and is widely used in several countries and regions.

Butyl cinnamate is an agent of mosquito repellent.

2-(4-Methylphenyl)-1-propanol (2-(P-tolyl)propan-1-ol) is an organic compound containing a benzene ring and a hydroxyl group, which is used in organic synthesis and biochemical experiments.

4-(1-Methoxyethyl)phenol is a phenol containing substituent groups and is used in organic synthesis and biochemical experiments.

Pseudopelletierine is the main alkaloid derived from the root-bark of Punica granatum, along with at least three other alkaloids: isopelletierine, methylpelleteirine (C9H17ON) and pelletierine, which yield 1.8, 0.01, 0.20 and 0.52 grams per kilogram of ra

D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(4)P1 can be formed by dephosphorylation of Ins(1,4)P2 by inositol polyphosphate 1-phosphatase or dephosphorylated to inositol by inositol monophosphatase.

Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lopez, J.A.V., Nogawa, T., Futamura, Y., et al.Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647J. Antibiot. (Tokyo)72(12)991-995(2019) 2.Ishida, S., Arai, M., Niikawa, H., et al.Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium speciesBiol. Pharm. Bull.34(6)917-920(2011) 3.Kalinovskaya, N.I., Romaneko, L.A., Irisawa, T., et al.Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activityMicrobiol. Res.166(8)654-661(2011) 4.Matsubara, K., Sakuda, S., Tanaka, M., et al.Morphological changes in insect BM-N4 cells induced by nocardamineBiosci. Biotechnol. Biochem.62(10)2049-2051(1998)

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4)-P1 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound contains the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. PtdIns-(4)-P1 can be phosphorylated to di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.

L319 (Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate) is a lipid membrane, a potential nucleic acid carrier.

Acetyl-coenzyme A (Acetyl-CoA) lithium, a membrane-impermeant central metabolic intermediate, is integral to the TCA cycle and oxidative phosphorylation, regulates cellular mechanisms by serving as the sole donor of acetyl groups for post-translational acetylation of proteins, and is a critical precursor in lipid synthesis [1] [2] [3] [4].

N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 . TT3 is an ionizable lipid-like materials for mRNA and CRISPR Cas9 delivery [1] [2] .

LNP Lipid-4 (Compound 8-8) is a lipid compound integral to the synthesis of lipid nanoparticle compositions, demonstrating potential for the transport of biologically active substances [1].

N-Boc-4-piperidinemethanol (Compound 4), an acetylcholinesterase (AChE) inhibitor, is utilized in the study of Alzheimer's Disease [1].

18:1 PI(4,5)P2 (1,2-Dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′,5′-bisphosphate) (ammonium)) is utilized as a biomaterial or organic compound in life sciences research.

18:0-20:4 PI(3,4,5)P3 is a reagent used in biochemical reactions.

08:0 PI(3,4)P2 is a reagent used in biochemical reactions.

1,2-Dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) ammonium is a membrane-associated signaling molecule that plays a crucial role in cell physiology. It is involved in regulating cell growth, metabolism, proliferation, and survival, and participates in various signal transduction pathways, significantly influencing intracellular signal transmission.

EDTA-(S)-1-(4-Aminoxyacetamidobenzyl) is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Konjac glucomannan (Viscosity≥15000mPa.s) is an acetylated (1-4)-β-D-glucomannan extracted from the tubers of Amorphophallus konjac or konjac root. In Japan, it serves as a dietary supplement intended to reduce calorie intake by expanding in water.

4-Amino-1-Boc-piperidine-4-carboxylic acid is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Galβ(1-3)GlcNAcβ(1-3)Galβ(1-4)Glc-β-pNP is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Gal[236Bn]β(1-4)Glc[236Bn]-β-MP is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.