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Results for "

antibacterial

" in TargetMol Product Catalog
  • Inhibitor Products
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Antibacterial agent 132
T72310
Antibacterial agent 132 showed antimicrobial activity against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibited aromatase enzyme with IC50 of 0.047 μM.
  • $195
In Stock
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Antibacterial agent 170
T500562163817-03-4
4-(4,5-dibromo-6-oxo-1,6-dihydropyridazin-1-yl)benzene-1-sulfonamide is a sulfonamide derivative used in the synthesis of building blocks for various supramolecular structures such as metal-organic skeletons and coordination polymers. It has antiproliferative activity against a variety of tumor cell lines.
  • $58
In Stock
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Antibacterial agent 171
T602051354546-42-1In house
(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide is a LpxC inhibitor with IC50 >95.2 nM.
  • $117
In Stock
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Antibacterial compound 1
T10500232951-56-3In house
Antibacterial compound 1 is an antibacterial compound.
  • $1,520
8-10 weeks
Size
QTY
TargetMol | Inhibitor Sale
Antibacterial agent 162 trifluoromethanesulfonate
T83099
Antibacterial agent 162 trifluoromethanesulfonate (compound 7), a dual-function molecule, demonstrates potent inhibitory effects on Staphylococcus aureus, encompassing MRSA strains, and exerts antiproliferative activity against colon cancer and non-small cell lung cancer cells. This compound is applicable in both anticancer and antibacterial research [1].
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Antibacterial agent 161 trifluoromethanesulfonate
T83100
Compound 6 (Antibacterial agent 161, trifluoromethanesulfonate) exhibits antibacterial properties and demonstrates significant antiproliferative effects against colon cancer and non-small cell lung cancer [1].
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Antibacterial agent 160
T831011854892-66-2
Antibacterial Agent 160 is a potent antibacterial agent that rapidly eradicates bacteria and inhibits the formation of bacterial biofilms. It disrupts the normal functioning of DNA, resulting in cellular death [1].
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Antibacterial agent 163
T83098
Antibacterial agent 163 (compound 1), a hydroxyquinoline derivative, potently inhibits methicillin-resistant Staphylococcus aureus (MRSA) [1].
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Antibacterial agent 165
T83097
Antibacterial agent 165 (compound 3), a hydroxyquinoline derivative, effectively inhibits methicillin-resistant Staphylococcus aureus (MRSA) [1], demonstrating its potent antibacterial properties.
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Antibacterial agent 66
T63027
Antibacterial agent 66 (Compound 6q) is a trifluoromethylpyridine 1,3,4-oxadiazole derivative active against Xanthomonas oryzae pv. oryzae (Xoo) (EC50: 7.2 μg/mL).
  • $1,520
10-14 weeks
Size
QTY
Antibacterial agent 37
T389381452459-04-9
Antibacterial agent 37 is an effective antimicrobial compound. It holds potential as a valuable tool for researching bacterial infections.
  • Inquiry Price
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Antibacterial agent 42
T388671426572-47-5
Antibacterial Agent 42 demonstrates potent antibacterial activity by effectively reducing the Minimum Inhibitory Concentration (MIC) of the broad-spectrum antibacterial agent Ceftazidime.
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Antibacterial agent 30
T403162694867-40-6
Antibacterial agent 30 exhibits remarkable in vitro activity against Xoo, as evidenced by its EC50 value of 1.9 μg/mL.
  • $1,520
Backorder
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QTY
Antibacterial agent 57
T388841426572-67-9
Antibacterial agent 57 (example 25) is a antibacterial agent.
  • Inquiry Price
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Antibacterial agent 88
T64054
Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.
  • $1,520
10-14 weeks
Size
QTY
Antibacterial agent 131
T72309
Antibacterial agent 131 is a compound with antibacterial properties.
  • $98
In Stock
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Antibacterial agent 92
T72350
Antibacterial agent 92, a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor, demonstrates a potent antibacterial effect by inhibiting Salmonella enterica threonyl-tRNA synthetase (SeThrRS) with an IC50 of 0.58 μM.
  • $1,970
8-10 weeks
Size
QTY
Antibacterial agent 63
T741652910919-43-4
Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to a siderophore mimetic.
  • $2,420
10-14 weeks
Size
QTY
Antibacterial agent 86
T74529
Compound A11 (Antibacterial agent 86) exhibits the highest bacteriostatic activity against methicillin-resistant S. aureus, with minimum inhibitory concentration (MIC) values reaching as low as 0.00191 μg/mL. This efficacy is 162 and 32 times greater than the commercial antibiotics tiamulin and retapamulin, respectively [1].
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Antibacterial agent 136
T74715
Antibacterial Agent 136 (Compound 3), an oxadiazolone antibiotic, exhibits high antibacterial potency against Methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) 50 value of 0.8 μM [1].
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Antibacterial agent 116
T7486699330-28-6
Antibacterial agent 116, a benzophenone-containing salicylanilide compound, exhibits potent antibacterial activity by inhibiting peptidoglycan formation. It is employed as a photoaffinity probe to label Acinetobacter baumannii penicillin-binding protein (PBP1b), thereby blocking the propagation pathway and disrupting the growth of the peptidoglycan chain.
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Antibacterial agent 128
T75001
Antibacterial Agent 128, a siderophore analog-Ciprofloxacin (Ciprofloxacin) conjugate connected via a cleavable linker, demonstrates effective antibiotic properties. Specifically, it exhibits activity against P. aeruginosa and B. pseudomallei, with Minimum Inhibitory Concentration (MIC) values ranging from 0.25 to 64 μg/mL and 1 to 32 μg/mL, respectively [1].
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Antibacterial agent 123
T749772615254-55-0
Antibacterial Agent 123 (Compound 111) serves as an effective membrane-disrupting agent targeting antibiotic-resistant Gram-positive bacteria [1].
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Antibacterial agent 75
T61799
Antibacterial agent 75 (compound 24) possesses antibacterial properties. Its notable attribute is the ability to re-sensitize VRSA (Vancomycin-Resistant Staphylococcus aureus) strains to vancomycin, as reported in reference [1].
  • $1,520
10-14 weeks
Size
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Antibacterial agent 46
T388711426572-51-1
Antibacterial agent 46, serves as a potent antibacterial compound. With its versatile properties, this agent demonstrates considerable potential for supporting research on bacterial infections.
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Antibacterial agent 101
T632692452306-15-7
Antibacterial agent 101 exhibited antibacterial and antifungal effects (MIC=4-32 μg/mL).
  • $2,140
6-8 weeks
Size
QTY
Antibacterial agent 98
T619112408695-41-8
Antibacterial agent 98 (compound g37) is an effective oral antibacterial agent, which can inhibit the ATPase activity of Gyrase B and weaken the DNA super-helix of S. aureus. Antibacterial agent 98 does not induce the development of MRSA (methicillin-resistant Staphylococcus aureus) resistance.
  • $1,520
6-8 weeks
Size
QTY
Antibacterial agent 33
T388761426572-59-9
Antibacterial Agent 33, a potent antibacterial compound, effectively decreases the minimum inhibitory concentration (MIC) of Ceftazidime, another antibacterial agent.
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Antibacterial agent 80
T60634
Antibacterial agent 80 (compound 20) has antibacterial activity [1].
  • $1,520
10-14 weeks
Size
QTY
Antibacterial agent 32
T389151436862-65-5
Antibacterial agent 32 exhibits potent antimicrobial activity against E. coli strains NCTC 13351, M 50, and 7 MP, with minimum inhibitory concentration (MIC) values of 1 mcg/mL, 2 mcg/mL, and 8 mcg/mL, respectively (WO2013030733A1, example 43).
  • Inquiry Price
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Antibacterial agent 62
T62910
Antibacterial agent 62 is a novel redox cycle anti-tuberculosis compound that exhibits significant bactericidal activity against growth and nutrient deficient phenotypically resistant non-growing bacteria.
  • $1,520
10-14 weeks
Size
QTY
Antibacterial agent 55
T388801426572-63-5
Antibacterial agent 55 (example 21) is a antibacterial agent.
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Antibacterial agent 48
T620921426572-53-3
Antibacterial agent 48 is an antimicrobial agent that reduces the MIC of the antimicrobial agent Ceftazidime.
  • $2,140
6-8 weeks
Size
QTY
Antibacterial agent 94
T612841666134-58-2
Antibacterial agent 94 (compound 5b) is a highly effective antibacterial agent that demonstrates strong activity against various bacterial strains. Notably, Antibacterial Agent 94 is capable of eradicating MRSA persisters, highlighting its potential as a therapeutic solution. Its mechanism of action involves interference with the bacterial membrane and disruption of the phosphatidylglycerol (PG) synthesis pathway [1].
  • $1,520
8-10 weeks
Size
QTY
Antibacterial agent 27 
T961265795-51-9
Antibacterial agent 27 has potent anti-Candida activity.
  • $74
In Stock
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TargetMol | Inhibitor Sale
Antibacterial agent 79
T62120
Antibacterial agent 79 is an antibacterial agent.
  • $1,520
10-14 weeks
Size
QTY
Antibacterial agent 157
T789002573134-85-5
Compound B12 (Antibacterial agent 157) is a fungicidal agent that can impact protein synthesis in Botrytis cinerea. It is utilized in research for controlling gray mold resistance [1].
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Antibacterial agent 141
T789762930013-56-0
Compound B14 (Antibacterial agent 141) exhibits antibacterial activity against the plant pathogens Xoo, Xac, Psa, and Cmm, with an EC50 value of 1.28 μM. It functions by inhibiting cell membrane formation and altering cell permeability.
  • $1,520
6-8 weeks
Size
QTY
Antibacterial agent 144
T79282
Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin. It acts by disrupting the bacterial cytoplasmic membrane and inhibiting biofilm formation. Additionally, it binds to human serum albumin (HSA) with a dissociation constant (Kd) of 13.2 μM, enhancing its bactericidal activity. This compound also forms a supramolecular complex with DNA, thereby hindering DNA replication [1].
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Antibacterial agent 154
T794092163048-45-9
Antibacterial Agent 154 (Compound 7), a Fluoroquinolone derivative, exhibits broad-spectrum efficacy against both Gram-positive and Gram-negative bacteria when administered orally. It has been shown to be effective in vivo using a mouse model of staphylococcal sepsis [1].
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Antibacterial agent 52
T388771426572-60-2
Antibacterial agent 52 (example 18) is a antibacterial agent.
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Antibacterial agent 111
T611232448358-84-5
Antibacterial agent 111 (Compound 3) exhibits potent antibacterial activity against B. cereus and K. pneumonia, with MIC values of 3.90 μg/mL and 0.49 μg/mL, respectively. It achieves this antibacterial effect by strongly binding to specific residues of tyrosyl-tRNA synthetase [1].
  • $1,520
6-8 weeks
Size
QTY
Antibacterial agent 99
T628802452306-13-5
Antibacterial agent 99 (compound 7b) is an effective antibacterial agent. antibacterial agent 99 has significant antibacterial and antifungal effects and no haemolytic activity.
  • $2,140
10-14 weeks
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Antibacterial agent 96
T611702413006-62-7
Antibacterial Agent 96 (Compound 4k) is a potent antibacterial and antitubercular compound effective against both drug-susceptible and multidrug-resistant Mycobacterium tuberculosis (M. tuberculosis) strains. However, it exhibits toxicity to HepG2 and Vero cells [1].
  • $1,520
6-8 weeks
Size
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Antibacterial agent 124
T723032304448-00-6
Antibacterial agent 124 is a potent inhibitor of bacterial prolyl-tRNA synthetase (ProRS), specifically targeting Staphylococcus aureus ProRS (Sa ProRS) with an inhibitory concentration (IC50) of 0.18 μM.
  • $1,520
6-8 weeks
Size
QTY
Antibacterial agent 12
T739112382921-99-3
Antibacterial agent 12, a biaryloxazolidinone analogue, effectively combats both antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria [1].
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Antibacterial agent 71
T74341
The compound demonstrates enhanced potency against wild-type (WT) strains of Escherichia coli, Acinetobacter baumannii, and Burkholderia cenocepacia, showing significant improvements of up to (>128-fold) due to increased outer-membrane permeability in hyperpermeable E. coli strains and S. Tm.
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Antibacterial agent 69
T62627
Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).
  • $1,520
10-14 weeks
Size
QTY
Antibacterial compound 2
T11427170104-58-2
Antibacterial compound 2 is a potent antimicrobial agent effective against many human veterinary pathogens, inhibiting multi-drug resistant staphylococci, enterococci and streptococci, as well as anaerobic bacteria.
  • $700
8-10 weeks
Size
QTY
Antibacterial agent 113
T63252
Antibacterial agent 113 was an effective antimicrobial agent (antibacterial) against P. aeruginosa, S. mutans, B. subtilis, E. coli, E. faecalis, S. typhimuriumand and S. aureus microorganisms exhibited antibacterial effects with MIC values of 15625 μM.
  • $1,520
10-14 weeks
Size
QTY