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Lysergol
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Catalog No. T15824Cas No. 602-85-7
Lysergol has been used as a hypotensive, psychotropic analgesic, and uterus- and intestine-stimulating drug. Lysergol is a clavinet alkaloid isolated from seeds of Ipomoea muricata and is a bioenhancer for the drugs and nutrients and has antibacterial activity.
Lysergol
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Purity: 99.63%
Catalog No. T15824Cas No. 602-85-7
Lysergol has been used as a hypotensive, psychotropic analgesic, and uterus- and intestine-stimulating drug. Lysergol is a clavinet alkaloid isolated from seeds of Ipomoea muricata and is a bioenhancer for the drugs and nutrients and has antibacterial activity.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $56 | In Stock | In Stock | |
| 10 mg | $91 | In Stock | In Stock | |
| 25 mg | $148 | In Stock | In Stock | |
| 50 mg | $223 | In Stock | In Stock | |
| 100 mg | $337 | In Stock | In Stock | |
| 200 mg | $498 | In Stock | In Stock | |
| 500 mg | $812 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $68 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.63%
Appearance:Solid
Color:Orange
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Product Introduction
Lysergol AI Summary
Lysergol shows a high binding affinity for the 5-hydroxytryptamine 1 (5-HT1) receptor with an IC50 value of 15.0 nM in rat cortical membrane homogenates, as determined by a radioligand binding assay. It also binds to the 5-hydroxytryptamine 2 (5-HT2) receptor in rat frontal cortex homogenates with an IC50 value of 160.0 nM, demonstrating selectivity for the 5-HT1 receptor over the 5-HT2 receptor with a selectivity ratio of 11.0. The compound exhibits a diverse range of bioactivities, including inhibition of several enzymes and proteins such as Ubiquitin-specific Protease USP2a, Jumonji Domain Containing 2E, and various others involved in processes like Tau fibril formation, DNA replication, and transcription. Moreover, it shows activity in cell-based assays related to both mouse and human receptors, including serotonin receptors and trace amine-associated receptor 1. However, in antiviral assays against SARS-CoV-2, Lysergol displayed an IC50 value greater than 20,000.0 nM in inhibiting virus-induced cytotoxicity in VERO-6 cells, indicating a lack of significant antiviral activity at the tested concentration..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Lysergol has been used as a hypotensive, psychotropic analgesic, and uterus- and intestine-stimulating drug. Lysergol is a clavinet alkaloid isolated from seeds of Ipomoea muricata and is a bioenhancer for the drugs and nutrients and has antibacterial activity. |
| Molecular Weight | 254.33 |
| Formula | C16H18N2O |
| Cas No. | 602-85-7 |
| Smiles | [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@@H](CO)CN2C)c34 |
| Relative Density. | 1.3 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (39.32 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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