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Synonyms:
Octyl decyldimethyl ammonium chloride
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | Octyl decyldimethyl ammonium chloride is a quaternary ammonium compound with antibacterial properties. It disrupts cell membranes, leading to cytotoxic effects. Additionally, Octyl decyldimethyl ammonium chloride poses a risk of skin irritation and stimulates the secretion of pro-inflammatory IL-1α. |
| In vitro | Octyl decyldimethyl ammonium chloride demonstrates antibacterial activity against Staphylococcus aureus within a timeframe of 0.25-60 minutes. Additionally, within 1-4 hours, it induces cytotoxicity in L929 murine fibroblasts. Moreover, exposure for 15 minutes to 48 hours significantly reduces the viability of recombinant human epidermal cells to 56% and enhances the secretion of pro-inflammatory IL-1α. |
| In vivo | Octadecyl dimethyl chlorohydrin ammonium (present in QAC#1) (1-5% w/w; local administration; single exposure; 4 hours) caused moderate skin irritation in female C57BL/6 N mice, with an average total irritation score of 1.7, and most of the test animals showed significant epidermal thickening. |
| Molecular Weight | 334.02 |
| Formula | C20H44ClN |
| Cas No. | 32426-11-2 |
| Smiles | [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCC |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 µL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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