e. coli — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T41078	Lipopolysaccharides, Escherichiacoli	Lipopolysaccharide, E. coli O111:B4	Others
	Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) is a unique component of the cell wall of Gram-negative bacteria, consisting of three regions: lipid A, oligosaccharide core and O-specific polysaccharide (O-antigen...		Others
T22269	Benzyldodecyldimethylammonium Chloride Dihydrate		Antibacterial
	Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aerugino...		Antibacterial
T1313	Nitrofurantoin	Furadantine,Macrodantin,Furadonine	Antibacterial , Antibiotic
	Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoi...		Antibacterial , Antibiotic
T36683	Vedaprofen	Quadrisol,PM 150,CERM 10202	COX , Antibacterial , Prostaglandin Receptor
	Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.		COX , Antibacterial , Prostaglandin Receptor
T9508	MONOCAPRYLIN	Sefsol 318,Glyceryl monocaprylate	Antibacterial
	Monocaprylin (Sefsol 318) is a monoglyceride of caprylic acid with an excellent antibacterial activity. Monocaprylin inhibits a variety of foodborne pathogenic and spoilage microorganisms and has the potential for an alt...		Antibacterial
T82462	Enterotoxin STp (E. coli)
	Enterotoxin STp (E. coli), a heat-stable enterotoxin, is applicable in vaccine research [1].
T19794	Temafloxacin	Omniflox	Antibiotic
	Temafloxacin (Omniflox) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.		Antibiotic
T1389	Dyclonine hydrochloride	Dyclocaine hydrochloride,Dyclonine HCl	Sodium Channel , Antibacterial , Antifungal
	Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .		Sodium Channel , Antibacterial , Antifungal
T8384	Gatifloxacin hydrochloride	AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride)	Topoisomerase , Antibacterial , Antibiotic
	Gatifloxacin hydrochloride (AM-1155 hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, which can inhibit the bacterial enzyme DNA rotase and topoisomerase IV.		Topoisomerase , Antibacterial , Antibiotic
T1100	Polymyxin B Sulfate	Aerosporin,PMB,Polymyxin B sulphate,Polymyxin B sulfate (1404-26-8 free base),Poly-RX	Antibacterial , Antibiotic
	Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Po...		Antibacterial , Antibiotic
T1293	Gatifloxacin	BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155	Topoisomerase , Antibacterial , Antibiotic
	Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.		Topoisomerase , Antibacterial , Antibiotic
T39912	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine	5'-O-DMT-dU	Others
	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive dUTP nucleotidohydrolase (dUTPase) inhibitor(Ki > 1 mM) in E. coli. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted t...		Others
T13477	β-Glucuronidase-IN-1		Antibacterial
	β-Glucuronidase-IN-1 is an E. coli β-glucuronidase (β-glucuronidase) inhibitor with a potent, selective, non-competitive, and orally active IC50 and Ki value of 283 nM and 164 nM, respectively, against E. coli β-glucuron...		Antibacterial
T12126	MUT056399	Fab-001	Antibacterial
	MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli (IC50s of 12 nM and 58 nM, respectively).		Antibacterial
T4913	Maleic acid		Endogenous Metabolite , Antibacterial
	Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of L. monocytogenes and E. coli.		Endogenous Metabolite , Antibacterial
T10347L	Apidaecin IB acetate	Apidaecin IB acetate (123276-94-8 Free base)	Others
	Apidaecin IB acetate is an insect antibacterial peptide. The minimum concentration of apidaecin IB acetate against Escherichia coli (E. coli ML35, o18k1h7 and ATCC 25922) is 8 μM.		Others
T22387	NSC 55655	5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione	Others
	NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) possesses antimicrobial and antioxidant activities and inhibits the proliferation of B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi , A. niger and C...		Others
T11227L	Eravacycline dihydrochloride	TP-434-046,TP-434 dihydrochloride	Antibacterial
	Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).		Antibacterial
TP1663L	CysHHC10 acetate	CysHHC10 acetate(1408311-03-4 free base)	Antibacterial
	CysHHC10 acetate shows antibacterial activities against both Gram-positive and Gram-negative bacteria with MIC of 10.1, 20.2, 2.5, and 1.3 mM for E. coli, P. aeruginosa, S. aureus, and S. epidermidis, respectively.		Antibacterial
T19146	5,6-Dihydrouridine		Endogenous Metabolite
	5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea.		Endogenous Metabolite