cac

cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM.

Amylin (AMY3) antagonist (IC50 = 0.3 μM). Protects neuronal cells from Aβ(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Aβ plaque number and total area in a mouse Alzheimer's disease model.

Cacaoidin, a glycosylated lantibiotic extracted from Streptomyces cacaoi, exhibits strong antibacterial effects against Gram-positive pathogens, notably Clostridium difficile [1].

parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid glands as a polypeptide containing

α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid was identified as possible dual inhibitors for hLTA4H and hLTC4S enzymes by the computer-aided methodology.

Aspartame (SC-18862), an artificial, non-carbohydrate sweetener, is aspartyl-phenylalanine-1-methyl ester.

L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo in mouse brain preparations. L-Allylglycine (1.2 mmol/kg, i.p.) induces convulsions and decreases GABA concentration throughout the cerebellum, pons, medulla, striatum, cortex, and hippocampus in mice. Chronic administration (3.2 μg/0.5 μl per hour for 13 days) of L-allylglycine in rats increases locomotor activity in an open field test and impairs attention in the 5-choice serial reaction time task (5CSRTT). In vitro, L-allylglycine inhibits GAD only when used at high concentrations (1-80 mM). The more potent in vivo activity can be attributed to metabolic conversion of L-allylglycine to 2-keto-4-pentanoic acid, a more potent convulsant and GAD inhibitor.

Z-Asp(OBzl)-OH (N-Cbz-L-Aspartic acid 4-benzyl ester) is an aspartic acid derivative.

Fmoc-L-aspartic acid (Fmoc-Asp-OH) is an aspartic acid derivative.

Fmoc-L-glutamic acid 5-tert-butyl ester (Fmoc-Glu(OtBu)-OH) is a glutamic acid derivative.

Boc-L-aspartic acid 4-benzyl ester (Boc-Asp(OBzl)-OH) is an aspartic acid derivative.

2-Amino-3-mercaptopropanoic acid hydrochloride hydrate is a cysteine derivative, widely used in biochemical experiments and drug synthesis research.

Glycyl-L-phenylalanine (Gly-L-Phe) is a dipeptide often used as a model peptide for peptide transport in tracheal epithelial cells, which is immediately degraded in mucosal fluids and can be used for skin aging and moisturizing.

β-Methyl L-aspartate hydrochloride (L-Aspartic acid β-methyl ester hydrochloride) is an aspartic acid derivative commonly used to synthesize various compounds and is related to body immunity and metabolism.

Boc-Lys(Boc)-OH is an amino acid derivative used in peptide synthesis, where the α-amino and ε-amino groups of lysine are protected by Boc groups.

Leucic acid (α-Hydroxyisocaproic acid) is an amino acid widely found in plants and animals that prevents muscle loss and is broken down into glucose.

2-Aminohexanoic acid (Norleucine) is a non-protein-derived L-amino acid, widely used in biochemical experiments and drug synthesis research.

(S)-2-((Carboxymethyl)amino)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66493 and the CAS number is 56857-47-7.

Fmoc-HIS-OH is a histidine derivative.

H-DL-Lys-OH HCl is the hydrochloride salt of lysine, widely used in biochemical experiments and drug synthesis research.

H-Glu(OMe)-OH, a glutamate derivative, is used in synthesizing various compounds and is associated with immune and metabolic processes in the body.

2-Amino-3-(2-chlorophenyl)propanoic acid (2-Chloro-DL-Phenylalanine) is a phenylalanine derivative involved in biometabolism.

Glutamyl-glutamic acid (Glu-glu) is an Interpeptide Bridge in the Murein of Some Micrococci and Arthrobacter sp..

Gamma-Methylleucine (2-Amino-3-tert-butylpropionic acid) is an auxiliary for copper-catalyzed asymmetric Michael reactions.