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EGLU

Name: EGLU
Brand: TargetMol
SKU: T11165
Price: 293 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11165Cas No. 170984-72-2

Alias (2S)-α-Ethylglutamic acid, (2S)-α-EGLU

EGLU ((2S)-α-Ethylglutamic acid) is a competitive mGluR-2 receptor antagonist with antidepressant activity and anti-injury effects, which can be used in the study of arthritis.

EGLU

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Purity: 99.98%

Catalog No. T11165Alias (2S)-α-Ethylglutamic acid, (2S)-α-EGLUCas No. 170984-72-2

EGLU ((2S)-α-Ethylglutamic acid) is a competitive mGluR-2 receptor antagonist with antidepressant activity and anti-injury effects, which can be used in the study of arthritis.

Pack Size	Price	Availability
1 mg	$293	In Stock
2 mg	$436	In Stock
5 mg	$722	In Stock
10 mg	$987	In Stock
25 mg	$1,520	In Stock
50 mg	$1,980	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.98%

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Product Introduction

Bioactivity

Description	EGLU ((2S)-α-Ethylglutamic acid) is a competitive mGluR-2 receptor antagonist with antidepressant activity and anti-injury effects, which can be used in the study of arthritis.
Targets&IC50	mGluR2:66 μM (Kd)
In vitro	EGLU (200 μM) selectively antagonizes -ACPD-induced inhibition of the monosynaptic component of DRVRP.[1]
Synonyms	(2S)-α-Ethylglutamic acid, (2S)-α-EGLU

Chemical Properties

Molecular Weight	175.18
Formula	C₇H₁₃NO₄
Cas No.	170984-72-2
Smiles	[C@](CCC(O)=O)(C(O)=O)(CC)N
Relative Density.	1.278 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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