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Anti-Siglec-5 Antibody (4E708)
🥰Excellent
Catalog No. TMAY-02063
Anti-Siglec-5 Antibody (4E708) is a Mouse antibody targeting Siglec-5. Anti-Siglec-5 Antibody (4E708) can be used in ELISA.
Anti-Siglec-5 Antibody (4E708)
Anti-Siglec-5 Antibody (4E708)
🥰Excellent
Catalog No. TMAY-02063
Anti-Siglec-5 Antibody (4E708) is a Mouse antibody targeting Siglec-5. Anti-Siglec-5 Antibody (4E708) can be used in ELISA.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Siglec-5 Antibody (4E708) is a Mouse antibody targeting Siglec-5. Anti-Siglec-5 Antibody (4E708) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 4E708 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SIGLEC5 (rh SIGLEC5; TMPY-03549; O15389; Met1-Thr 434). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is also expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human SIGLEC5 Protein (TMPY-03549) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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