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Anti-Siglec-5 Antibody (3K993)

🥰Excellent
Catalog No. TMAY-02066

Anti-Siglec-5 Antibody (3K993) is a Rabbit antibody targeting Siglec-5. Anti-Siglec-5 Antibody (3K993) can be used in FCM.

Anti-Siglec-5 Antibody (3K993)

Anti-Siglec-5 Antibody (3K993)

🥰Excellent
Catalog No. TMAY-02066
Anti-Siglec-5 Antibody (3K993) is a Rabbit antibody targeting Siglec-5. Anti-Siglec-5 Antibody (3K993) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-Siglec-5 Antibody (3K993) is a Rabbit antibody targeting Siglec-5. Anti-Siglec-5 Antibody (3K993) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
3K993
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human SIGLEC5(CD170) expression on human whole blood granulocytes. Cells were stained with purified anti-Human SIGLEC5(CD170), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human SIGLEC5 (rh SIGLEC5; TMPY-03549; O15389; Met1-Thr 434).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is also expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
FITC/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human SIGLEC5 Protein (TMPY-03549)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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