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tβri

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  • Inhibitors & Agonists
    3
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    TargetMol | Compound_Libraries
Galunisertib
LY2157299
T2510700874-72-2
Galunisertib (LY2157299) is a TGF-β receptor type I (TGF-βRI) inhibitor (IC50=56 nM) that is selective. Galunisertib has antitumor activity and can be used in combination with PD-1 inhibitors.
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TargetMol | Inhibitor Hot
LY2109761
T2123700874-71-1
LY2109761 is a novel selective TGF-β receptor type I II (RI II) dual inhibitor with Ki of 38 nM and 300 nM, respectively; shown to negatively affect the phosphorylation of Smad2.
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LY-580276
T69212476475-07-7
LY-580276 is an inhibitor of the type I transforming growth factor beta receptor (RI).
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6-8 weeks
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