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Anti-Natriuretic Peptide Receptor C Antibody (8K442)

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Catalog No. TMAB-09254

Anti-Natriuretic Peptide Receptor C Antibody (8K442) is a Mouse antibody targeting Natriuretic Peptide Receptor C. Anti-Natriuretic Peptide Receptor C Antibody (8K442) can be used in WB.

Anti-Natriuretic Peptide Receptor C Antibody (8K442)

Anti-Natriuretic Peptide Receptor C Antibody (8K442)

😃Good
Catalog No. TMAB-09254
Anti-Natriuretic Peptide Receptor C Antibody (8K442) is a Mouse antibody targeting Natriuretic Peptide Receptor C. Anti-Natriuretic Peptide Receptor C Antibody (8K442) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Natriuretic Peptide Receptor C Antibody (8K442) is a Mouse antibody targeting Natriuretic Peptide Receptor C. Anti-Natriuretic Peptide Receptor C Antibody (8K442) can be used in WB.
Ig Type
IgG1, k
Clone
8K442
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNatriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Natriuretic Peptide Receptor C
Antigen Species
Human
Gene Name
NPR3
Gene ID
Protein Name
Atrial natriuretic peptide receptor 3
Uniprot ID
Function
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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