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Anti-Natriuretic Peptide Receptor C Antibody (8K442) is a Mouse antibody targeting Natriuretic Peptide Receptor C. Anti-Natriuretic Peptide Receptor C Antibody (8K442) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
| Description | Anti-Natriuretic Peptide Receptor C Antibody (8K442) is a Mouse antibody targeting Natriuretic Peptide Receptor C. Anti-Natriuretic Peptide Receptor C Antibody (8K442) can be used in WB. |
| Ig Type | IgG1, k |
| Clone | 8K442 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Natriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. |
| Immunogen | KLH conjugated synthetic peptide: human Natriuretic Peptide Receptor C |
| Antigen Species | Human |
| Gene Name | NPR3 |
| Gene ID | |
| Protein Name | Atrial natriuretic peptide receptor 3 |
| Uniprot ID | |
| Function | Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. |
| Molecular Weight | Theoretical: 57 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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