Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-ALK-4/ACVR1B Antibody (3Y53)

😃Good
Catalog No. TMAY-00990
Alias SKR2, ALK4, ACVRLK4, ACTRIB, activin A receptor, type IB

Anti-ALK-4/ACVR1B Antibody (3Y53) is a Mouse antibody targeting ALK-4/ACVR1B. Anti-ALK-4/ACVR1B Antibody (3Y53) can be used in ELISA.

Anti-ALK-4/ACVR1B Antibody (3Y53)

Anti-ALK-4/ACVR1B Antibody (3Y53)

😃Good
Catalog No. TMAY-00990Alias SKR2, ALK4, ACVRLK4, ACTRIB, activin A receptor, type IB
Anti-ALK-4/ACVR1B Antibody (3Y53) is a Mouse antibody targeting ALK-4/ACVR1B. Anti-ALK-4/ACVR1B Antibody (3Y53) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μL$198 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-ALK-4/ACVR1B Antibody (3Y53) is a Mouse antibody targeting ALK-4/ACVR1B. Anti-ALK-4/ACVR1B Antibody (3Y53) can be used in ELISA.
AliasSKR2, ALK4, ACVRLK4, ACTRIB, activin A receptor, type IB
Ig Type
Monoclonal Mouse IgG1
Clone
3Y53
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALK4 extracellular domain (rh ALK4; TMPY-01293; NP_004293.1; Met 1-Glu 126). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer of activin or activin like ligands signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. The known type II activin receptors include ActRII and ActRIIB, while the main type I activin receptor in mammalian cells is ALK-4 (ActRIB). In the presence of activin, type II and type I receptors form complexes whereby the type II receptors activate ALK-4 through phosphorylation. The activated ALK-4, in turn, transduces signals downstream by phosphorylation of its effectors, such as Smads, to regulate gene expression and affect cellular phenotype. ALK-4/ACVR1B is an important regulator of vertebrate development, with roles in mesoderm induction, primitive streak formation, gastrulation, dorsoanterior patterning, and left-right axis determination.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human ALK4 protein (TMPY-01293)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-ALK-4/ACVR1B Antibody (3Y53) | purchase Anti-ALK-4/ACVR1B Antibody (3Y53) | Anti-ALK-4/ACVR1B Antibody (3Y53) cost | order Anti-ALK-4/ACVR1B Antibody (3Y53)