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Anti-ALK-4/ACVR1B Antibody (3Y53) (Synonyms: SKR2, ALK4, ACVRLK4, ACTRIB, activin A receptor, type IB)

Name: Anti-ALK-4/ACVR1B Antibody (3Y53)
Brand: TargetMol
SKU: TMAY-00990
Rating: 4.5 (1 reviews)

Catalog No. TMAY-00990 Copy Product Info

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Anti-ALK-4/ACVR1B Antibody (3Y53) is a Mouse antibody targeting ALK-4/ACVR1B. Anti-ALK-4/ACVR1B Antibody (3Y53) can be used in ELISA.

Anti-ALK-4/ACVR1B Antibody (3Y53)

Copy Product Info

🥰Excellent

Catalog No. TMAY-00990

Synonyms SKR2, ALK4, ACVRLK4, ACTRIB, activin A receptor, type IB

Anti-ALK-4/ACVR1B Antibody (3Y53) is a Mouse antibody targeting ALK-4/ACVR1B. Anti-ALK-4/ACVR1B Antibody (3Y53) can be used in ELISA.

Anti-ALK-4/ACVR1B Antibody
(3Y53)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$198	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-ALK-4/ACVR1B Antibody (3Y53) is a Mouse antibody targeting ALK-4/ACVR1B. Anti-ALK-4/ACVR1B Antibody (3Y53) can be used in ELISA.
Synonyms	SKR2, ALK4, ACVRLK4, ACTRIB, activin A receptor, type IB
Ig Type	Mouse IgG1
Clone	3Y53
Reactivity	Human
Specificity	Human ALK4/ACVR1B No cross-reactivity in ELISA with Human ACTRII / ACVR2 / ACVR2A Human ACVR2B / ACTRIIB
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALK4 extracellular domain (rh ALK4; TMPY-01293; NP_004293.1; Met 1-Glu 126). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer of activin or activin like ligands signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. The known type II activin receptors include ActRII and ActRIIB, while the main type I activin receptor in mammalian cells is ALK-4 (ActRIB). In the presence of activin, type II and type I receptors form complexes whereby the type II receptors activate ALK-4 through phosphorylation. The activated ALK-4, in turn, transduces signals downstream by phosphorylation of its effectors, such as Smads, to regulate gene expression and affect cellular phenotype. ALK-4/ACVR1B is an important regulator of vertebrate development, with roles in mesoderm induction, primitive streak formation, gastrulation, dorsoanterior patterning, and left-right axis determination.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human ALK4 protein (TMPY-01293)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

SKR-2SKR 2ALK-4ALK 4ACVRLK-4ACVRLK 4

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