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Anti-TRIM5 Monoclonal Antibody (1S383)
(Synonyms: TRIM5alpha, RNF88) Copy Product Info
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Synonyms: TRIM5alpha, RNF88
Catalog No. TMAT-1532 Copy Product Info
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Anti-TRIM5 Monoclonal Antibody (1S383) is a Mouse antibody targeting TRIM5. Anti-TRIM5 Monoclonal Antibody (1S383) can be used in WB,IHC.
Anti-TRIM5 Monoclonal Antibody
(1S383)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TRIM5 Monoclonal Antibody (1S383) is a Mouse antibody targeting TRIM5. Anti-TRIM5 Monoclonal Antibody (1S383) can be used in WB,IHC. |
| Synonyms | TRIM5alpha, RNF88 |
| Ig Type | IgG1 |
| Clone | 1S383 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human trim5 alpha expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TRIM5 |
| Gene ID | |
| Protein Name | Tripartite motif-containing protein 5 |
| Uniprot ID |
| Molecular Weight | Theoretical: 56.3 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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