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Anti-ACVR1 Monoclonal Antibody (8B228)
(Synonyms: TSRI, SKR1, FOP, ALK2, ACVRLK2, ACVR1A, ACTRI) Copy Product Info
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Synonyms: TSRI, SKR1, FOP, ALK2, ACVRLK2, ACVR1A, ACTRI
Catalog No. TMAT-0024 Copy Product Info
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Anti-ACVR1 Monoclonal Antibody (8B228) is a Mouse antibody targeting ACVR1. Anti-ACVR1 Monoclonal Antibody (8B228) can be used in IHC,IF,FCM.
Anti-ACVR1 Monoclonal Antibody
(8B228)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-ACVR1 Monoclonal Antibody (8B228) is a Mouse antibody targeting ACVR1. Anti-ACVR1 Monoclonal Antibody (8B228) can be used in IHC,IF,FCM. |
| Synonyms | TSRI, SKR1, FOP, ALK2, ACVRLK2, ACVR1A, ACTRI |
| Ig Type | IgG1 |
| Clone | 8B228 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ACVR1 (AA: 21-120) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ACVR1 |
| Gene ID | |
| Protein Name | Activin receptor type-1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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