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TriGalNAc CBz

Name: TriGalNAc CBz
Brand: TargetMol
SKU: T77945
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77945Cas No. 186613-57-0

TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.

TriGalNAc CBz

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Purity: 98.13%

Catalog No. T77945Cas No. 186613-57-0

TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$30	In Stock	In Stock
5 mg	$45	In Stock	In Stock
10 mg	$68	In Stock	In Stock
25 mg	$139	In Stock	In Stock
50 mg	$233	In Stock	In Stock
100 mg	$377	In Stock	In Stock
200 mg	$532	-	In Stock
1 mL x 10 mM (in DMSO)	$62	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.13%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.

Chemical Properties

Molecular Weight	633.64
Formula	C₃₄H₃₅NO₁₁
Cas No.	186613-57-0
Smiles	O(C(=O)C1=CC=CC=C1)[C@H]2[C@@H](OC(=O)C3=CC=CC=C3)[C@@H](COC(=O)C4=CC=CC=C4)O[C@@H](OCCCCC(O)=O)[C@@H]2NC(C)=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (126.25 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5782 mL	7.8909 mL	15.7818 mL	78.9092 mL
5 mM	0.3156 mL	1.5782 mL	3.1564 mL	15.7818 mL
10 mM	0.1578 mL	0.7891 mL	1.5782 mL	7.8909 mL
20 mM	0.0789 mL	0.3945 mL	0.7891 mL	3.9455 mL
50 mM	0.0316 mL	0.1578 mL	0.3156 mL	1.5782 mL
100 mM	0.0158 mL	0.0789 mL	0.1578 mL	0.7891 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc