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TriGalNAc CBz

🥰Excellent
Catalog No. T77945Cas No. 186613-57-0

TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.

TriGalNAc CBz

TriGalNAc CBz

🥰Excellent
Purity: 98.13%
Catalog No. T77945Cas No. 186613-57-0
TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$30In StockIn Stock
5 mg$45In StockIn Stock
10 mg$68In StockIn Stock
25 mg$139In StockIn Stock
50 mg$233In StockIn Stock
100 mg$377In StockIn Stock
200 mg$532-In Stock
1 mL x 10 mM (in DMSO)$62In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.13%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.
Chemical Properties
Molecular Weight633.64
FormulaC34H35NO11
Cas No.186613-57-0
SmilesO(C(=O)C1=CC=CC=C1)[C@H]2[C@@H](OC(=O)C3=CC=CC=C3)[C@@H](COC(=O)C4=CC=CC=C4)O[C@@H](OCCCCC(O)=O)[C@@H]2NC(C)=O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (126.25 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5782 mL7.8909 mL15.7818 mL78.9092 mL
5 mM0.3156 mL1.5782 mL3.1564 mL15.7818 mL
10 mM0.1578 mL0.7891 mL1.5782 mL7.8909 mL
20 mM0.0789 mL0.3945 mL0.7891 mL3.9455 mL
50 mM0.0316 mL0.1578 mL0.3156 mL1.5782 mL
100 mM0.0158 mL0.0789 mL0.1578 mL0.7891 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LYTACs
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