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Tricin 7-O-glucoside
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Catalog No. TN5547Cas No. 32769-01-0
Alias Tricin 7-glucoside
Tricin 7-O-glucoside is a naturally occurring flavonoid with antidepressant and anxiolytic properties that increases the activity time of mice in the forced swim test. It protects the brain by attenuating brain I/R damage and attenuating blood-brain barrier (BBB) disruption, decreasing HMGB1 and NF-κB signaling pathways.
Tricin 7-O-glucoside
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Purity: 99.23%
Catalog No. TN5547Alias Tricin 7-glucosideCas No. 32769-01-0
Tricin 7-O-glucoside is a naturally occurring flavonoid with antidepressant and anxiolytic properties that increases the activity time of mice in the forced swim test. It protects the brain by attenuating brain I/R damage and attenuating blood-brain barrier (BBB) disruption, decreasing HMGB1 and NF-κB signaling pathways.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $564 | - | In Stock | |
| 5 mg | $1,729 | Inquiry | Inquiry | |
| 1 mL x 10 mM (in DMSO) | $1,980 | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.23%
Appearance:Solid
Color:White
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Product Introduction
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Chemical Properties
Storage & Solubility Information
| Description | Tricin 7-O-glucoside is a naturally occurring flavonoid with antidepressant and anxiolytic properties that increases the activity time of mice in the forced swim test. It protects the brain by attenuating brain I/R damage and attenuating blood-brain barrier (BBB) disruption, decreasing HMGB1 and NF-κB signaling pathways. |
| In vivo | Methods: The organic fraction (PcEA) was obtained from the hydroalcoholic extract of the aerial parts of P. coriacea and then subjected to chemical analysis and separation to obtain six fractions (PcEA, T1, T2, T1.1, T2.1 and T2.2). Male ICR mice were used to determine the antidepressant activity of the selected treatments (PcEA, T1, T2 and T1.1) based on the forced swim test (FST). The anxiolytic-like effects of various treatments (PcEA, T1, T2, T2.1 and T2.2) were determined using the elevated plus maze (EPM) test. Results: The organic fraction of P. coriacea reduced the anxiety-like behavior of mice and increased the activity time in the FST. After chemical separation, two compounds with antidepressant activity and anxiolytic-like effects were isolated from the species, namely T1.1 (Tricin 7-O-glucoside) and T2.2 (harmane). [1] |
| Synonyms | Tricin 7-glucoside |
| Molecular Weight | 492.43 |
| Formula | C23H24O12 |
| Cas No. | 32769-01-0 |
| Smiles | O=C1C=2C(OC(=C1)C3=CC(OC)=C(O)C(OC)=C3)=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=CC2O |
| Relative Density. | 1.582 g/cm3 (Predicted) |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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