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Riamilovir

Name: Riamilovir
Brand: TargetMol
SKU: T8904
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8904Cas No. 123606-06-4

Alias Triazavirin, 7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-one

Riamilovir (7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-one) is a broad-spectrum antiviral drug candidate.

Riamilovir

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Purity: 99.84%

Catalog No. T8904Alias Triazavirin, 7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-oneCas No. 123606-06-4

Riamilovir (7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-one) is a broad-spectrum antiviral drug candidate.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$30	In Stock	In Stock
5 mg	$60	In Stock	In Stock
10 mg	$103	In Stock	In Stock
25 mg	$181	In Stock	In Stock
50 mg	$268	In Stock	In Stock
100 mg	$373	In Stock	In Stock
200 mg	$513	-	In Stock
1 mL x 10 mM (in DMSO)	$62	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.84%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Riamilovir AI Summary

Riamilovir exhibits antiviral activity against Hantaan 76-118 and pseudotyped recombinant vesicular stomatitis virus delta G Gn-Gc. It demonstrates a higher selective index for Hantaan 76-118, indicating a more favorable CC50 to IC50 ratio compared to that for vesicular stomatitis virus delta G Gn-Gc. The compound displays cytotoxicity towards MDCK and HEK293T cells, though this occurs at different concentration thresholds for each cell type..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Riamilovir (7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-one) is a broad-spectrum antiviral drug candidate.
Synonyms	Triazavirin, 7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-one

Chemical Properties

Molecular Weight	228.19
Formula	C₅H₄N₆O₃S
Cas No.	123606-06-4
Smiles	O=C1N2C(NC(SC)=N2)=NN=C1N(=O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (1095.58 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3823 mL	21.9116 mL	43.8231 mL	219.1156 mL
5 mM	0.8765 mL	4.3823 mL	8.7646 mL	43.8231 mL
10 mM	0.4382 mL	2.1912 mL	4.3823 mL	21.9116 mL
20 mM	0.2191 mL	1.0956 mL	2.1912 mL	10.9558 mL
50 mM	0.0876 mL	0.4382 mL	0.8765 mL	4.3823 mL
100 mM	0.0438 mL	0.2191 mL	0.4382 mL	2.1912 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc