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Anti-Atezolizumab Antibody (9K295)

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Catalog No. TMAS-00009
Alias Tecentriq

Anti-Atezolizumab Antibody (9K295) is a Mouse antibody targeting Atezolizumab. Anti-Atezolizumab Antibody (9K295) can be used in ELISA.

Anti-Atezolizumab Antibody (9K295)

Anti-Atezolizumab Antibody (9K295)

😃Good
Catalog No. TMAS-00009Alias Tecentriq
Anti-Atezolizumab Antibody (9K295) is a Mouse antibody targeting Atezolizumab. Anti-Atezolizumab Antibody (9K295) can be used in ELISA.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
40 μg$3057-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Atezolizumab Antibody (9K295) is a Mouse antibody targeting Atezolizumab. Anti-Atezolizumab Antibody (9K295) can be used in ELISA.
SynonymsTecentriq
Ig Type
IgG1,κ
Clone
9K295
Specificity
The product is specific for Atezolizumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody Anti-Atezolizumab Antibody (1C27) (TMAS-00008).
Application
Recommended Dose
ELISA: 0.01-1 µg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
PurificationProtein A affinity column
AppearanceLyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
FormulationLyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Research BackgroundAtezolizumab is a fully humanized, engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1). Atezolizumab blocks the interaction of PD-L1 with programmed cell death protein 1 (PD-1) and CD80 receptors (B7-1Rs). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by atezolizumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as "immune checkpoint inhibition."
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Biotin
Antibody Types Available
2
Antigen Details
Immunogen
Atezolizumab
Chemical Properties
Stability & Storage
Stability & StorageThe lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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