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Anti-Sestrin 1 Antibody (3U236)
(Synonyms: Sestrin1, SEST1, SEST 1, sesn1, PA26) Copy Product Info
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Synonyms: Sestrin1, SEST1, SEST 1, sesn1, PA26
Catalog No. TMAS-00453 Copy Product Info
🥰Excellent
Anti-Sestrin 1 Antibody (3U236) is a Rabbit antibody targeting Sestrin 1. Anti-Sestrin 1 Antibody (3U236) can be used in FCM, WB.
Anti-Sestrin 1 Antibody
(3U236)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $369 | 7-10 days | 7-10 days | |
| 100 µL | $677 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-Sestrin 1 Antibody (3U236) is a Rabbit antibody targeting Sestrin 1. Anti-Sestrin 1 Antibody (3U236) can be used in FCM, WB. |
| Synonyms | Sestrin1, SEST1, SEST 1, sesn1, PA26 |
| Ig Type | IgG |
| Clone | 3U236 |
| Reactivity | Human,Mouse,Rat |
| Specificity | Sestrin 1 |
| Verified Activity | Western blot analysis of SESN1 expression in K562 cell lysate. |
| Application | |
| Recommended Dose | FCM: 1:20-1:100; WB: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Supplied in 10 mM phosphate buffered saline, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Research Background | Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized peptide: human Sestrin 1 |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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