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Anti-Sestrin 1 Antibody (3U236)
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Catalog No. TMAS-00453
Alias Sestrin1, SEST1, SEST 1, sesn1, PA26
Anti-Sestrin 1 Antibody (3U236) is a Rabbit antibody targeting Sestrin 1. Anti-Sestrin 1 Antibody (3U236) can be used in FCM, WB.
Anti-Sestrin 1 Antibody (3U236)
Anti-Sestrin 1 Antibody (3U236)
😃Good
Catalog No. TMAS-00453Alias Sestrin1, SEST1, SEST 1, sesn1, PA26
Anti-Sestrin 1 Antibody (3U236) is a Rabbit antibody targeting Sestrin 1. Anti-Sestrin 1 Antibody (3U236) can be used in FCM, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $369 | 7-10 days | 7-10 days | |
| 100 μL | $677 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Sestrin 1 Antibody (3U236) is a Rabbit antibody targeting Sestrin 1. Anti-Sestrin 1 Antibody (3U236) can be used in FCM, WB. |
| Synonyms | Sestrin1, SEST1, SEST 1, sesn1, PA26 |
| Ig Type | IgG |
| Clone | 3U236 |
| Reactivity | Human,Mouse,Rat |
| Specificity | Sestrin 1 |
| Verified Activity | Western blot analysis of SESN1 expression in K562 cell lysate. |
| Application | |
| Recommended Dose | FCM: 1:20-1:100; WB: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Supplied in 10 mM phosphate buffered saline, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Research Background | Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized peptide: human Sestrin 1 |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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