Shopping Cart
Remove All
Your shopping cart is currently empty
Masilukast
Copy Product Info
🥰Excellent
Catalog No. T27979Cas No. 136564-68-6
Alias ZD-3523, SA-09012, MCC-847, ICI-D-3523, ICI D-3523, D-3523
Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation.
Masilukast
Copy Product Info🥰Excellent
Purity: 99.62%
Catalog No. T27979Alias ZD-3523, SA-09012, MCC-847, ICI-D-3523, ICI D-3523, D-3523Cas No. 136564-68-6
Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $316 | In Stock | In Stock | |
| 5 mg | $708 | In Stock | In Stock | |
| 10 mg | $948 | In Stock | In Stock | |
| 25 mg | $1,410 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:99.62%
ee:100%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
Masilukast AI Summary
Masilukast exhibits bioactivity related to leukotriene receptors, specifically LTD4, with potent inhibition constants for displacing LTD4 on guinea pig lung parenchymal membranes and binding to LTE4 on guinea pig tracheal spirals. It effectively inhibits LTD4-induced dyspnea in guinea pigs via both oral and intravenous administration. The compound displays selectivity for receptors such as Thromboxane 2 and Prostaglandin 1. Additionally, its oral bioavailability and clearance rates have been evaluated in various animal models, including rats, guinea pigs, and dogs. Notably, the ratio of its effective doses administered orally versus intravenously is 52.0, indicating a significant difference in bioactivity depending on the route of administration..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation. |
| Synonyms | ZD-3523, SA-09012, MCC-847, ICI-D-3523, ICI D-3523, D-3523 |
| Molecular Weight | 615.66 |
| Formula | C31H32F3N3O5S |
| Cas No. | 136564-68-6 |
| Smiles | C(C=1C=2C(N(C)C1)=CC=C(C(NC[C@@H](CC(F)(F)F)C)=O)C2)C3=C(OC)C=C(C(NS(=O)(=O)C4=C(C)C=CC=C4)=O)C=C3 |
| Relative Density. | 1.31g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (81.21 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Masilukast | purchase Masilukast | Masilukast cost | order Masilukast | Masilukast chemical structure | Masilukast formula | Masilukast molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.