synthesis

Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity.

G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic that selectively inhibits eukaryotic protein synthesis by blocking peptide chain elongation.

Methyl 3-aminopropanoate hydrochloride (β-Alanine methyl ester hydrochloride) is the ethyl ester of the non-essential amino acid β-alanine.

Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prokaryotic and eukaryotic cells for Neo resistance genes.

Puromycin dihydrochloride (CL13900 dihydrochloride) is a cinnamamide adenosine antibiotic and an inhibitor of protein synthesis. Puromycin dihydrochloride inhibits protein synthesis by binding to RNA and has antitumor and antitrypanosomal activity.

Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, widely used in studying DNA binding anticancer agents and DNA binding agents that regulate DNA structure and function.

Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic or eukaryotic cells transfected with hph or hyg resistance genes.

Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus. Orellanine strongly inhibits the synthesis of macromolecules (Proteins, RNA and DNA) in Madin-Darby canine kidney cells and in rat liver mitochondria.

Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autophagy and apoptosis.

Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.

Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibiting ribonucleic acid synthesis. Vancomycin can be used for the treatment of serious infections for which all antibiotics have failed.

Arachidonic acid (Immunocytophyte) is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.

Blasticidin S HCl is a peptide-based nucleoside antibiotic (antibiotic) isolated from Streptomyces griseochromogenes that inhibits prokaryotic and eukaryotic protein synthesis by interfering with the formation of peptide bonds in the ribosome.

Cycloheximide (Naramycin A) is a natural product that reversibly inhibits translation elongation, is an antimitotic compound, and is an inhibitor of DNA and protein synthesis.

Vinaxanthone (SM-345431) is a small molecule compound derived from Penicillium chrysogenum that acts as a selective and potent inhibitor of semaphorin3A, phospholipase C (PLC), and FabI, exhibiting antimicrobial activity by blocking intracellular fatty acid synthesis and inhibiting the growth of Staphylococcus aureus.

Lathosterol, a molecule akin to cholesterol, serves as a biomarker for the body's total cholesterol synthesis, as indicated by its serum concentration.

Holomycin (N-Demethylthiolutin) is a secondary metabolite of dithiopyrrolidone. HolomycinHolomycin, an antibiotic secondary metabolite, is required for the biofilm formation of natural photogenic Bacillus galatheae S2753 and is also a broad-spectrum antibiotic. holomycin promotes biofilm formation of S2753 through its alene-disthionyl group. Holomycin has antitumor activity and is involved in RNA synthesis.

Cis-N-Feruloyltyramine is a naturally occurring compound found in various plants that shows cytotoxicity against the P-388 cancer cell line. Cis-N-Feruloyltyramine is an inhibitor of in vitro prostaglandin (PG) synthesis.

1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.

Elaidic acid (trans-Oleic Acid) is the 9-trans isomer of oleic acid. It is a monounsaturated trans-fatty acid which can be found in partially hydrogenated cooking oils. In human platelets incubated with arachidonic acid, elaidic acid inhibits HHT and HETE formation while inducing prostaglandin and thromboxane synthesis.

Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs), which act as transcription factors that promote cell differentiation and apoptosis. This naturally occurring retinoic acid has potential antineoplastic activity, exhibits immunomodulatory and anti-inflammatory responses, and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization.

Solanesol (Betulanonaprenol) is a phytochemical present in tobacco leaf. Starting material for synthesis of co-enzyme Q10. Exhibits antiulcer activity.

Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.

2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the actin cytoskeleton for the control of root elongation and cell production.