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Hexane-1,6-diol is a diol commonly employed to dissolve liquid-liquid phase separation precipitates. It impairs kinase and phosphatase activity and partially inhibits DNA polymerase.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 g | $29 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | - | In Stock |
| Description | Hexane-1,6-diol is a diol commonly employed to dissolve liquid-liquid phase separation precipitates. It impairs kinase and phosphatase activity and partially inhibits DNA polymerase. |
| In vitro | The monoesters and diesters of hexane-1,6-diol act as substrates in in vitro digestion studies of pancreatic lipase, showing two degradation pathways: hydrolysis and transesterification [1]. Hexane-1,6-diol can be lactonized by alcohol dehydrogenases like AaSDR-1 to produce ε-caprolactone, and its conversion process is affected by the buffer solution [2]. |
| Molecular Weight | 118.17 |
| Formula | C6H14O2 |
| Cas No. | 629-11-8 |
| Smiles | OCCCCCCO |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 160 mg/mL (1353.98 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween-80+45% Saline: 5 mg/mL (42.31 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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