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N-butyryl-L-Homoserine lactone-d5

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Catalog No. T89693Cas No. 2701379-46-4

N-Butyryl-L-Homoserine lactone-d5 is a deuterated version of N-Butanoyl-L-homoserine lactone. Serving as a cleavable ADC linker, N-Butanoyl-L-homoserine lactone (C4-HSL) is employed in the synthesis of antibody-drug conjugates (ADCs). This compound also exhibits antimicrobial activity, making it useful in combating bacterial biofilms. Additionally, N-Butanoyl-L-homoserine lactone aptamers are employed to inhibit quorum sensing and prevent the formation of Pseudomonas aeruginosa biofilms.

N-butyryl-L-Homoserine lactone-d5

N-butyryl-L-Homoserine lactone-d5

😃Good
Catalog No. T89693Cas No. 2701379-46-4
N-Butyryl-L-Homoserine lactone-d5 is a deuterated version of N-Butanoyl-L-homoserine lactone. Serving as a cleavable ADC linker, N-Butanoyl-L-homoserine lactone (C4-HSL) is employed in the synthesis of antibody-drug conjugates (ADCs). This compound also exhibits antimicrobial activity, making it useful in combating bacterial biofilms. Additionally, N-Butanoyl-L-homoserine lactone aptamers are employed to inhibit quorum sensing and prevent the formation of Pseudomonas aeruginosa biofilms.
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Product Introduction

Bioactivity
Description
N-Butyryl-L-Homoserine lactone-d5 is a deuterated version of N-Butanoyl-L-homoserine lactone. Serving as a cleavable ADC linker, N-Butanoyl-L-homoserine lactone (C4-HSL) is employed in the synthesis of antibody-drug conjugates (ADCs). This compound also exhibits antimicrobial activity, making it useful in combating bacterial biofilms. Additionally, N-Butanoyl-L-homoserine lactone aptamers are employed to inhibit quorum sensing and prevent the formation of Pseudomonas aeruginosa biofilms.
Chemical Properties
Molecular Weight176.23
FormulaC8H13NO3
Cas No.2701379-46-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

ADCLinkerADC Linker
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