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Thalidomide-NH-amido-C6-NH2
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Catalog No. T208134Cas No. 2763827-13-8
Thalidomide-NH-amido-C6-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, consisting of a cereblon ligand derived from Thalidomide and a linker, which can be utilized in the synthesis of PROTAC.
Thalidomide-NH-amido-C6-NH2
🥰Excellent
Catalog No. T208134Cas No. 2763827-13-8
Thalidomide-NH-amido-C6-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, consisting of a cereblon ligand derived from Thalidomide and a linker, which can be utilized in the synthesis of PROTAC.
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Chemical Properties
| Description | Thalidomide-NH-amido-C6-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, consisting of a cereblon ligand derived from Thalidomide and a linker, which can be utilized in the synthesis of PROTAC. |
| Molecular Weight | O=C(NCCCCCCN)CNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3 |
| Formula | C21H27N5O5 |
| Cas No. | 2763827-13-8 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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