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(S,R,S)-AHPC-PEG6-Tos

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Catalog No. T206142Cas No. 2839806-94-7

(S, R, S)-AHPC-PEG6-Tos is a compound combining a VHL recruiter ligand and a polyethylene glycolated crosslinker with a tosyl group. The tosyl group serves as a good leaving group in nucleophilic substitution reactions. (S, R, S)-AHPC-PEG2-Tos is applicable in the synthesis of PROTAC compounds and for molecules designed for targeted protein degradation.

(S,R,S)-AHPC-PEG6-Tos

(S,R,S)-AHPC-PEG6-Tos

😃Good
Catalog No. T206142Cas No. 2839806-94-7
(S, R, S)-AHPC-PEG6-Tos is a compound combining a VHL recruiter ligand and a polyethylene glycolated crosslinker with a tosyl group. The tosyl group serves as a good leaving group in nucleophilic substitution reactions. (S, R, S)-AHPC-PEG2-Tos is applicable in the synthesis of PROTAC compounds and for molecules designed for targeted protein degradation.
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Product Introduction

Bioactivity
Description
(S, R, S)-AHPC-PEG6-Tos is a compound combining a VHL recruiter ligand and a polyethylene glycolated crosslinker with a tosyl group. The tosyl group serves as a good leaving group in nucleophilic substitution reactions. (S, R, S)-AHPC-PEG2-Tos is applicable in the synthesis of PROTAC compounds and for molecules designed for targeted protein degradation.
Chemical Properties
Molecular Weight877.075
FormulaC42H60N4O12S2
Cas No.2839806-94-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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