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Sulfo-NHS-Acetate sodium

Name: Sulfo-NHS-Acetate sodium
Brand: TargetMol
SKU: T212713
Rating: 4.5 (1 reviews)

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Catalog No. T212713Cas No. 221222-61-3

Sulfo-NHS-Acetate sodium is a PROTAC linker belonging to the alkyl chain class and is used in the synthesis of PROTAC molecules.

Sulfo-NHS-Acetate sodium

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Catalog No. T212713Cas No. 221222-61-3

Sulfo-NHS-Acetate sodium is a PROTAC linker belonging to the alkyl chain class and is used in the synthesis of PROTAC molecules.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Sulfo-NHS-Acetate sodium is a PROTAC linker belonging to the alkyl chain class and is used in the synthesis of PROTAC molecules.
In vitro	PROTAC consists of two distinct ligands connected by a Linker, with one ligand targeting the E3 ubiquitin ligase and the other binding to a target protein. PROTAC leverages the ubiquitin-proteasome system within cells to selectively degrade the target protein.

Chemical Properties

Molecular Weight	259.17
Formula	C₆H₆NNaO₇S
Cas No.	221222-61-3
Smiles	O=C(C)ON1C(CC(S(=O)([O-])=O)C1=O)=O.[Na+]

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc