cle — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T69514	CLE-030
	CLE-030 is a KCNQ2 agonist. CLE030 stably binds to the central cavity. Functional analysis, molecular dynamics simulations, and calculations of the potential of mean force revealed that the carbonyl oxygen of CLE030 inf...
T39113L	Povorcitinib phosphate		JAK
	Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the treatment of cutaneous lupus erythematosus and Lichen planus.		JAK
TJS1183	Cyclen	1,4,7,10-tetraazacyclododecane	Others
	Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.		Others
T7330	Nucleozin		Influenza Virus
	Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.		Influenza Virus
T63808	Cap-dependent endonuclease-IN-1		Others
	Cap-dependent endonuclease-IN-1 is a highly potent and orally active cap-dependent endonuclease inhibitor with antiviral activity for the study of influenza virus infection.		Others
T0147	Clemastine fumarate	HS-592 (fumarate),Meclastine fumarate,Meclastine (fumarate)	Autophagy , Histamine Receptor
	Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.		Autophagy , Histamine Receptor
T4721	β-Nicotinamide mononucleotide	β-NM	Others , Endogenous Metabolite
	β-Nicotinamide mononucleotide (β-NM) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD...		Others , Endogenous Metabolite
T5375	Loreclezole		GABA Receptor
	Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.		GABA Receptor
T77753	EBV lytic cycle inducer-1	Dp44mT	Antifection
	EBV lytic cycle inducer-1 is an iron chelate analogue that induces the lytic cycle of EBV.		Antifection
T78345	Ribonuclease A	EC 3.1.27.5,RNase A
	Ribonuclease A (RNase A) is a potent endonuclease that removes RNA during dna and protein preparation.
T5067	Flavin adenine dinucleotide disodium salt	Flavin Adenine Dinucleotide Disodium,FAD sodium salt,FAD-Na2	Others , Endogenous Metabolite
	Flavin adenine dinucleotide disodium salt (FAD sodium salt) is a flavin dinucleotide that is synthesized when the AMP moiety from ATP is transferred onto riboflavin 5'-monophosphate. FAD functions as a coenzyme that faci...		Others , Endogenous Metabolite
T16684	Puromycin aminonucleoside	NSC 3056	Apoptosis , Proteasome , Aminopeptidase , Antibacterial , Antibiotic
	Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.
T9582	CLEFMA		NF-κB
	CLEFMA has anti-proliferative activity. CLEFMA inhibits tumor growth associated with NF-κB-regulated anti-inflammatory and anti-metastatic effects.		NF-κB
T1822L	Clemizole hydrochloride		HCV Protease , Histamine Receptor
	Clemizole hydrochloride is an antagonist for H1 histamine receptor. According to the research, Clemizole hydrochloride can inhibit hepatitis C virus (HCV) replication and NS4B's RNA binding.		HCV Protease , Histamine Receptor
T8206	Cycleanine		Others
	Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.		Others
T0999	Clevidipine	Clevidipine butyrate,Cleviprex	Calcium Channel , AChR
	Clevidipine (Clevidipine butyrate) is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.		Calcium Channel , AChR
T19966	Clemastine	HS-592,Mecloprodin,Meclastin,HS592,HS 592	Histamine Receptor
	Clemastine (Meclastin) is an antagonist of the H1 receptor and exhibits anti-inflammatory effects.		Histamine Receptor
TN1511	Cleomiscosin A		LDL , Antioxidant , TNF
	Cleomiscosin A is derived from Acer okamotoanum leaf and twig and shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. Cleomiscosin A can be used in studies about the prevention of LDL oxidat...		LDL , Antioxidant , TNF
TN1730	Heraclenol		Antibacterial
	Heraclenol is derived from the fruits of Angelica lucida with antibacterial activities. Heraclenol is a germination inhibitor in the parsley and lettuce seeds.		Antibacterial
TN1507	Clematichinenoside AR		TNF , Autophagy
	Clematichinenoside AR exerts anti-inflammatory and immunosuppressive properties, it has anti-arthritic effects on PI3K/Akt signaling pathway and TNF-α± associated with collagen-induced arthritis.		TNF , Autophagy