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Synonyms: CLEC4K
Anti-CD207 Monoclonal Antibody
(8T576)

| Description | Anti-CD207 Monoclonal Antibody (8T576) is a Mouse antibody targeting CD207. Anti-CD207 Monoclonal Antibody (8T576) can be used in FCM. |
| Synonyms | CLEC4K |
| Ig Type | IgG2b |
| Clone | 8T576 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD207 (AA: extra 155-328) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CD207 |
| Gene ID | |
| Protein Name | C-type lectin domain family 4 member K |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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