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Anti-CD207 Monoclonal Antibody (8T576)

(Synonyms: CLEC4K) Copy Product Info
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Synonyms: CLEC4K

Catalog No. TMAT-0323 Copy Product Info
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Anti-CD207 Monoclonal Antibody (8T576) is a Mouse antibody targeting CD207. Anti-CD207 Monoclonal Antibody (8T576) can be used in FCM.

Anti-CD207 Monoclonal Antibody
(8T576)

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Product Introduction

Bioactivity
Description
Anti-CD207 Monoclonal Antibody (8T576) is a Mouse antibody targeting CD207. Anti-CD207 Monoclonal Antibody (8T576) can be used in FCM.
SynonymsCLEC4K
Ig Type
IgG2b
Clone
8T576
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThe protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CD207 (AA: extra 155-328) expressed in E. Coli.
Antigen Species
Human
Gene Name
CD207
Gene ID
Protein Name
C-type lectin domain family 4 member K
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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