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Synonyms:
Anti-Human CD47 Antibody
(B6H12, humanized)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $182 | - | In Stock | |
| 5 mg | $539 | - | In Stock | |
| 10 mg | $863 | - | In Stock |
| Description | Anti-Human CD47 Antibody (B6H12, humanized) is an antibody that specifically targets human CD47 and is suitable for immunological and oncological research related to CD47-mediated immune evasion, macrophage-associated signal transduction, and cell surface checkpoint regulation. |
| In vitro | Anti-Human CD47 Antibody (B6H12, humanized) (10 μg/mL, 2 h) increases macrophage phagocytosis of HepG2 and H3B cells[1].
Anti-Human CD47 Antibody (B6H12, humanized) (10 μg/mL, 2 h) decreases the proliferation and attenuates cell migration and invasion abilityof IOMM-Lee cells[2]. Anti-Human CD47 Antibody (B6H12, humanized) (10 μg/mL, 2 h) decreases invasion in osteosarcoma cells and increases macrophage phagocytosis of osteosarcoma tumor cells[3]. |
| In vivo | Anti-Human CD47 Antibody (B6H12, humanized) (100 μg, i.p.; daily for 5 weeks) reduces tumor growth in IOMM-Lee tumor mouse models[2].
Anti-CD47 Antibody (B6.H12) (100 μg, i.p.; three times weekly) restrains tumor progression in osteosarcoma mouse models[3]. |
| Clone | B6H12 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD47 |
| Molecular Weight | 144.40 kDa (Predicted) |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature, -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Size | Quantity | Unit Price | Amount | Operation |
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