dna — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13592	Calf thymus DNA	DNA from calf thymus, Thymonucleic acid	DNA/RNA Synthesis
	Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, which can be widely used in the study of DNA binding anticancer agents and ...		DNA/RNA Synthesis
T80644	DNA polymerase-IN-1		Antiviral , DNA/RNA Synthesis
	DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an I...		Antiviral , DNA/RNA Synthesis
T31554	DNA-Spermidine	DA-51,DA 51,DA51,DNA Spermidine
	DNA-spermidine influences the activity of restricted endonuclease from several bacterial species.
T3103	L67	DNA Ligase Inhibitor	DNA , DNA/RNA Synthesis
	L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).		DNA , DNA/RNA Synthesis
T1904	SGI-1027	DNA Methyltransferase Inhibitor II,SGI1027	Apoptosis , DNA Methyltransferase
	SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027(SGI1027) against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively.		Apoptosis , DNA Methyltransferase
T2433	NU 7026	NU7026,DNA-PK Inhibitor II,LY293646	Apoptosis , ATM/ATR , DNA-PK , PI3K
	NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition against both ATM and ATR.		Apoptosis , ATM/ATR , DNA-PK , PI3K
T27194	DNA Primase Inhibitor-13
	DNA Primase Inhibitor-13 is a novel inhibitor of DNA primase.
T79922	Taq DNA polymerase		DNA/RNA Synthesis
	Taq DNA polymerase is a thermostable enzyme utilized in polymerase chain reactions (PCR) to amplify DNA sequences [1].		DNA/RNA Synthesis
T63681	DNA Gyrase-IN-1
	DNA Gyrase-IN-1 is a potent and selective DNA promoter inhibitor (IC50: 2.6 μM). DNA Gyrase-IN-1 inhibits Mycobacterium tuberculosis (Mtb) activity well (MIC: 0.49 μM). DNA Gyrase-IN-1 can be used to study tuberculosis.
T74337	DNA crosslinker 1 dihydrochloride
	DNA Crosslinker 1 (dihydrochloride) serves as a potent binder for the DNA minor groove, exhibiting a DNA binding affinity (ΔTm) of 1.1°C. This compound is utilized in research focused on anticancer therapies [1].
T78712	DNA Gyrase-IN-8		DNA/RNA Synthesis
	DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].		DNA/RNA Synthesis
T79165	DNA-PK-IN-10		DNA-PK
	DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell lung cancer [1].		DNA-PK
T79308	DNA polymerase-IN-3		DNA/RNA Synthesis
	DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in proliferative disease research [1].		DNA/RNA Synthesis
T61751	DNA-PK-IN-3
	DNA-PK-IN-3 is a highly potent inhibitor of DNA-PK. This compound exerts a synergistic effect when combined with radiotherapy and chemotherapy, resulting in enhanced therapeutic outcomes and significant inhibition of tum...
T74339	DNA crosslinker 3 dihydrochloride
	DNA Crosslinker 3 (dihydrochloride) (Compound 1) is a potent minor groove binder, exhibiting a DNA binding affinity (ΔTm) of 1.4°C, and serves as a valuable tool in anticancer research [1].
T74340	DNA crosslinker 4 dihydrochloride
	DNA Crosslinker 4 (dihydrochloride) is a potent binder of the DNA minor groove with inhibitory effects on cancer cell lines NCI-H460, A2780, and MCF-7. It is utilized in research for anticancer applications [1].
T81953	LANA-DNA-IN-2
	Compound 20, also known as LANA-DNA-IN-2, is an inhibitor of the interaction between latency-associated nuclear antigen (LANA) and DNA. It is employed in the study of Kaposi’s sarcoma-associated herpesvirus (KSHV) infect...
T82536	DNA polymerase-IN-4
	DNA polymerase-IN-4 (Compd 5c), a coumarin derivative, exhibits antiretroviral activity, achieving an IC50 of 134.22 μM [1].
T74848	DNA Gyrase-IN-6
	Antibacterial agent 138, a benzothiazole inhibitor, targets bacterial DNA gyrase and topoisomerase IV, exhibiting both favorable solubility and plasma protein binding. It demonstrates antibacterial activity against Gram-...
T61937	DNA Gyrase-IN-3
	DNA Gyrase-IN-3 (Compound 28) is an inhibitor of bacterial DNA gyrase B. The IC50 of DNA Gyrase-IN-3 inhibits Escherichia coli DNA rotatase is 5.41-15.64 μM. DNA Gyrase-IN-3 shows anti-tuberculosis and antibacterial acti...