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Anti-PRKDC Monoclonal Antibody (7M587)
(Synonyms: XRCC7, PRKDC, p350, HYRC1, HYRC, DNPK1, DNA-PKcs, DNAPK) Copy Product Info
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Synonyms: XRCC7, PRKDC, p350, HYRC1, HYRC, DNPK1, DNA-PKcs, DNAPK
Catalog No. TMAT-1174 Copy Product Info
😃Good
Anti-PRKDC Monoclonal Antibody (7M587) is a Mouse antibody targeting PRKDC. Anti-PRKDC Monoclonal Antibody (7M587) can be used in IHC,IF.
Anti-PRKDC Monoclonal Antibody
(7M587)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-PRKDC Monoclonal Antibody (7M587) is a Mouse antibody targeting PRKDC. Anti-PRKDC Monoclonal Antibody (7M587) can be used in IHC,IF. |
| Synonyms | XRCC7, PRKDC, p350, HYRC1, HYRC, DNPK1, DNA-PKcs, DNAPK |
| Ig Type | IgG1 |
| Clone | 7M587 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PRKDC expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PRKDC |
| Gene ID | |
| Protein Name | DNA-dependent protein kinase catalytic subunit |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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