ODN 1826

Name: ODN 1826
Brand: TargetMol
SKU: T74509
Price: 299 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T74509Cas No. 202668-42-6

Alias ODN-1826, ODN1826

ODN 1826 is a 20-mer DNA strand, a TLR9 agonist and an immunostimulant, with anti-tumor and cardioprotective effects, promoting apoptosis, and stimulating the production of NO and iNOS. ODN 1826 is a CpG DNA mimetic that can be used as an adjuvant for synthetic vaccines.

ODN 1826

🥰Excellent

Catalog No. T74509Alias ODN-1826, ODN1826Cas No. 202668-42-6

Pack Size	Price	Availability	Quantity
1 mg	$299	In Stock

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Bioactivity

Description	ODN 1826 is a 20-mer DNA strand, a TLR9 agonist and an immunostimulant, with anti-tumor and cardioprotective effects, promoting apoptosis, and stimulating the production of NO and iNOS. ODN 1826 is a CpG DNA mimetic that can be used as an adjuvant for synthetic vaccines.
In vivo	Eight to twelve week old C57BL/6J wild-typ (WT) mice. To determine the required ODN 1826 concentration for a proinflammatory response, WT mice were injected intravenously (i.v.) with 3nM, 10nM, or 30nM ODN 1826 suspended in 200μl phosphate buffered saline (PBS) or vehicle (PBS). Dose-dependent IL-6 induction and 30nM ODN 1826 led to the highest IL-6 formation. [1]
Synonyms	ODN-1826, ODN1826

Chemical Properties

Cas No.	202668-42-6
Color	White
Appearance	Solid

Storage & Solubility Information

Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: 50 mg/mL, Sonication is recommended.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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