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DNA

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    1962
    TargetMol | Activity
  • Compound Libraries
    15
    TargetMol | inventory
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    44
    TargetMol | natural
  • Inhibitory Antibodies
    5
    TargetMol | composition
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    99
    TargetMol | Activity
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    28
    TargetMol | inventory
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    311
    TargetMol | natural
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    15
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    345
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    38
    TargetMol | inventory
L67
T3103325970-71-6
L67 (DNA Ligase Inhibitor) is a competitive inhibitor of human DNA ligases I and III with an IC50 of 10 μM.
  • $42
In Stock
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QTY
TargetMol | Inhibitor Sale
Calf thymus DNA
T1359291080-16-9
Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, widely used in studying DNA binding anticancer agents and DNA binding agents that regulate DNA structure and function.
  • $33
In Stock
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Aristolochic acid B
T7031475-80-9
Aristolochic acid B (Aristolochic Acid II) is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, Aristolochic acid B shows more carcinogenic risk than aristolochic acid I, and this may be, at least partly, the result of its increased levels in kidney and plasma.
  • $72
In Stock
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QTY
TargetMol | Inhibitor Hot
Carboxy-pyridostatin 2HCl
T30745L In house
Carboxy-pyridostatin 2HCl has potential antitumor activity with high affinity for DNA at DNA G4s.
  • $228
In Stock
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QTY
BTB09089
T67892245728-44-3In house
BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8 GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production in T cells and macrophages.
  • $65
In Stock
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Cyclophosphamide hydrate
T07076055-19-2
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.
  • $33
In Stock
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TargetMol | Citations Cited
3,7,4'-Trihydroxyflavone
TN21432034-65-3
3,7,4'-Trihydroxyflavone(5-Deoxykampferol) is a DNA-breaking flavonoid isolated from rosewood heartwood. It inhibits osteoclast differentiation, actin ring formation, and bone resorption in RAW 264.7 cells and bone marrow macrophages induced by NF-κB ligand (RANKL) receptor activators.
  • $81
In Stock
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Chromium picolinate
T457514639-25-9
Chromium picolinate causes DNA damage and mutation. It is an activator of p38.
  • $41
In Stock
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TargetMol | Citations Cited
Cyclophosphamide
T0707L50-18-0
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
  • $35
In Stock
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TargetMol | Citations Cited
Norharmane
T4024244-63-3
Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.
  • $30
In Stock
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Hydroxychloroquine sulfate
T0951747-36-4
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa.
  • $48
In Stock
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TargetMol | Citations Cited
Methoxsalen
T1548298-81-7
Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methoxsalen is by means of Photosensitizing Activity.
  • $29
In Stock
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TargetMol | Inhibitor Sale
Quinacrine dihydrochloride
T094269-05-6
Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities.
  • $41
In Stock
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TargetMol | Citations Cited
BCL6-IN-3
T104872253878-44-1
BCL6-IN-3 is a potent BCL6 inhibitor with GI50 of 70 nM in SU-DHL4 cells. BCL6-in-3 regulates cell activation, differentiation, DNA damage and apoptosis, and has antitumor activity.
  • $117
In Stock
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XR 5944
T35187343247-32-5In house
XR 5944 is an antitumor compound that targets DNA, is a topoisomerase inhibitor, inhibits ER activity, and can be used to study colon and lung cancer.
  • $293
In Stock
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4-Ethylcatechol
T775631124-39-6
4-Ethylcatechol is present in red wine and can be extracted from Glechoma longituba (NaKai) Kupr.4-Ethylcatechol induces DNA damage in the presence of Cu(II).4-Ethylcatechol is a potent antiplatelet compound.
  • $40
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Tallimustine HCl
T68151L118438-45-2In house
Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia.
  • $195
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L82
T60753329227-30-7In house
L82 is a DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM) that is selective and non-competitive.L82 expresses anti-proliferative activity against breast cancer cells.
  • $64
In Stock
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RU.521
T54862262452-06-0
RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
  • $41
In Stock
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TargetMol | Citations Cited
L189
T451764232-83-3
L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).
  • $35
In Stock
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TargetMol | Inhibitor Sale
AGI-24512
T141412201066-53-5
AGI-24512 is a potent inhibitor of methionine adenylyltransferase 2α (MAT2A) (IC50: 8 nM).AGI-24512 shows antiproliferative activity in MTAP-deficient cancer cells.AGI-24512 inhibits MAT2A, which causes DNA damage in MTAP, and is often used in conjunction with anticancer compounds in cancer research.
  • $132
In Stock
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Azoxymethane
T7371925843-45-2
Azoxymethane (AOM) is a DNA damaging agent that induces cancer and can be used in mouse models of colorectal cancer.
  • $313
In Stock
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Pterine-6-carboxylic acid
TN6988948-60-7
Pterine-6-carboxylic acid (6-Carboxypterin) is a photodegradation product of folic acid, which can be used as a photosensitive agent to study the molecular mechanism of UVA breaking DNA structure.
  • $117
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Dibenz[a,h]anthracene
T3142553-70-3
Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell cultures.
  • $50
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Gemcitabine monophosphate sodium salt hydrate
T41871638288-31-9
Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.
  • $198
Backorder
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G150
T113442369751-30-2
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
  • $135
In Stock
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DNA polymerase-IN-1
T80644809234-33-1In house
DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an IC50 of less than 250 μM. DNA polymerase-IN-1 was shown to inhibit Taq DNA polymerase by RT- DNA polymerase-IN-1 showed antiretroviral activity in vitro by RT-PCR assay and can be used to study oxidative damage and colorectal cancer.
  • $195 TargetMol
In Stock
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DNA gyrase B-IN-3
T787762412834-56-9
DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, functions as an inhibitor of bacterial DNA gyrase B and demonstrates antibacterial activity against Gram-positive strains [1].
  • $1,670
8-10 weeks
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DNA polymerase-IN-2
T79307
DNA polymerase-IN-2 (Compd 3c), a coumarin derivative, inhibits Taq DNA polymerase with an IC50 value of 48.25 μM and shows potential for value-added disease research [1].
  • Inquiry Price
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DNA Primase Inhibitor-13
T27194261363-54-6
DNA Primase Inhibitor-13 is a novel inhibitor of DNA primase.
  • $1,520
6-8 weeks
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DNA-PK-IN-3
T617512734846-19-4
DNA-PK-IN-3 is a highly potent inhibitor of DNA-PK that exerts a synergistic effect with radiotherapy and chemotherapy, enhancing therapeutic outcomes and significantly inhibiting tumor growth. Additionally, it demonstrates remarkable efficacy in reducing damage to normal cells, thereby minimizing adverse side effects, making it a compound of great potential for cancer research applications[1].
  • $2,140
6-8 weeks
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DNA crosslinker 3 dihydrochloride
T743392761734-21-6
DNA Crosslinker 3 (dihydrochloride) (Compound 1) is a potent minor groove binder, exhibiting a DNA binding affinity (ΔTm) of 1.4°C, and serves as a valuable tool in anticancer research [1].
  • $1,970
10-14 weeks
Size
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DNA Gyrase-IN-3
T619372522667-08-7
DNA Gyrase-IN-3 (Compound 28) is an inhibitor of bacterial DNA gyrase B with an IC50 of 5.41-15.64 μM for inhibiting Escherichia coli DNA rotatase. It exhibits both anti-tuberculosis and antibacterial activity.
  • $2,140
6-8 weeks
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14α-Demethylase/DNA Gyrase-IN-1
T62792
14α-Demethylase DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase DNA Gyrase, exhibiting antibacterial activity.
  • $1,520
10-14 weeks
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DNA gyrase B-IN-1
T64012
DNA gyrase B-IN-1 is a potent inhibitor of DNA gyrase B, exhibiting good binding affinity and stability. DNA gyrase B-IN-1 inhibits P. aeruginosa/i> DNA gyrase B (IC50: 2.2 μM).
  • $1,520
10-14 weeks
Size
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DNA-PK-IN-1
T626482663850-40-4
DNA-PK-IN-1, a potent inhibitor of DNA-PK, holds potential for cancer disease research.
  • $2,140
6-8 weeks
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DNA-PK-IN-2
T616332665720-22-7
DNA-PK-IN-2 is a highly effective inhibitor of DNA-dependent protein kinase (DNA-PK), an enzyme complex comprising the Ku70 Ku80 heterodimer and DNA-PK catalytic subunit (DNA-PKcs). It shows potential applications in cancer research, making it a valuable tool for studying cancer diseases [1].
  • $1,520
10-14 weeks
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DNA-PK-IN-12
T862892792146-91-7
DNA-PK-IN-12 (compound 31t), an orally active inhibitor of DNA-PK, demonstrates potent inhibition with an IC 50 of 0.1 nM. It effectively impedes Hct116 cell growth and colony formation, displaying an IC 50 of 33.28 μM, and exhibits antitumor activity in vivo [1].
  • Inquiry Price
10-14 weeks
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QTY
DNA polymerase-IN-3
T79308381689-75-4
DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, inhibits Taq DNA polymerase and shows potential applications in proliferative disease research [1].
  • Inquiry Price
8-10 weeks
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QTY
LANA-DNA-IN-2
T81953
Compound 20, also known as LANA-DNA-IN-2, is an inhibitor of the interaction between latency-associated nuclear antigen (LANA) and DNA. It is employed in the study of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection [1].
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DNA Gyrase-IN-1
T63681
DNA Gyrase-IN-1 is a potent and selective DNA promoter inhibitor (IC50: 2.6 μM). DNA Gyrase-IN-1 inhibits Mycobacterium tuberculosis (Mtb) activity well (MIC: 0.49 μM). DNA Gyrase-IN-1 can be used to study tuberculosis.
  • $1,520
10-14 weeks
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DNA-PK-IN-8
T618282823369-81-7
DNA-PK-IN-8 is a potent, selective, and orally active inhibitor of DNA-dependent protein kinase (DNA-PK) with an IC50 value of 0.8 nM, demonstrating synergistic antiproliferative effects across various cancer cell lines and significantly reducing HL-60 tumor growth when combined with Doxorubicin [1].
  • $1,520
10-14 weeks
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DNA crosslinker 1 dihydrochloride
T743372761734-27-2
DNA Crosslinker 1 (dihydrochloride) serves as a potent binder for the DNA minor groove, exhibiting a DNA binding affinity (ΔTm) of 1.1°C. This compound is utilized in research focused on anticancer therapies [1].
  • $1,970
10-14 weeks
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DNA Gyrase-IN-6
T74848
Antibacterial agent 138, a benzothiazole inhibitor, targets bacterial DNA gyrase and topoisomerase IV, exhibiting both favorable solubility and plasma protein binding. It demonstrates antibacterial activity against Gram-positive and Gram-negative strains and functions as a dual GyrB and ParE inhibitor [1].
  • Inquiry Price
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DNA Gyrase-IN-7
T862862925308-68-3
DNA Gyrase-IN-7 (compound 6d), a new inhibitor of Microbial DNA-Gyrase, is described in reference [1].
  • Inquiry Price
10-14 weeks
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QTY
DNA Gyrase-IN-9
T78866
DNA Gyrase-IN-9 (compound 4j), an antibacterial agent, selectively targets DNA gyrase and exhibits a minimum inhibitory concentration (MIC) of 0.5-2 µg mL for Gram-positive bacteria inhibition and a minimum bactericidal concentration (MBC) of 2-8 µg mL for Gram-positive bacteria eradication. Notably, this compound hinders DNA gyrase activity in Staphylococcus aureus with an IC50 of 6.29 µg mL [1].
  • Inquiry Price
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DNA-PK-IN-10
T791652919315-89-0
DNA-PK-IN-10 is a DNA-PK inhibitor used in breast cancer and non-small cell lung cancer research [1].
  • Inquiry Price
8-10 weeks
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DNA-PK-IN-9
T61533
DNA-PK-IN-9 (also known as compound YK6) is a highly potent inhibitor of DNA-dependent protein kinase (DNA-PK), displaying an IC50 value of 10.47 nM. DNA-PK-IN-9 holds significant potential in anticancer research [1].
  • $1,520
10-14 weeks
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