Search Result

Search Results for " esi "

Targets

DNA/RNA Synthesis Kinesin Bombesin Receptor cAMP

193

Compounds

123

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T11234	ESI-08		cAMP
	ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.		cAMP
T2244	ESI-09		cAMP , Virus Protease
	ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.		cAMP , Virus Protease
T15247	ESI-05	NSC 116966	cAMP
	ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.		cAMP
T76831	Tesidolumab	LFG316	Complement System
	Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cutting of C5 and preventing the subsequent formation of membrane...		Complement System
T12399	Peldesine	BCX 34	Nucleoside Antimetabolite/Analog , HIV Protease
	Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferation with an IC50 of 800 nM. Peldesine can be used in resear...		Nucleoside Antimetabolite/Analog , HIV Protease
T26778	Besipirdine	HP 749 free base,P-867493,P867493,HP 749,HP749,P 867493	Sodium Channel , Adrenergic Receptor
	Besipirdine (HP 749 free base) is a non-receptor-dependent cholinomimetic compound with alpha-adrenergic and cardiovascular activities.Besipirdine inhibits voltage-dependent sodium-potassium channels and inhibits biogeni...		Sodium Channel , Adrenergic Receptor
T39994	Sovilnesib	AMG650	Microtubule Associated
	Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.		Microtubule Associated
T19389	L-Ascorbic acid 2-phosphate magnesium	2-Phospho-L-ascorbic acid magnesium	Phosphatase , Phosphorylase
	L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production.It is a long-acting vitamin C derivative that can stimulate...		Phosphatase , Phosphorylase
T10491	Galidesivir	BCX4430,Immucillin-A	Others
	Galidesivir (BCX4430) is a broad-spectrum antiviral compound, an adenosine analog that inhibits viral RNA-dependent RNA polymerase (RdRp) activity.Galidesivir inhibits a wide range of RNA viral pathogens in vitro, and re...		Others
T4512	Magnesium glycinate	magnesium 2-aminoacetate,Magnesium diglycinate	Others
	Magnesium glycinate (magnesium 2-aminoacetate) is a supplement that boost magnesium levels in people with a deficiency of the mineral. Magnesium is a vital nutrient for regulating many body processes, including muscle an...		Others
T12834	Saroglitazar Magnesium		Others
	Saroglitazar Magnesium is a novel peroxissome proliferator-activated receptor (PPAR) agonist with significant activation activity against PPARα (EC50 0.65pM) and moderate activation against PPARγ (EC50 3 nM).		Others
T6405	Bepotastine Besilate	Talion,TAU 284,Bepreve,Bepotastine Beslilate	Histamine Receptor
	Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).		Histamine Receptor
T3258	Ponesimod	ACT-128800	S1P Receptor , LPL Receptor
	Ponesimod (ACT-128800) is an orally available sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) agonist with potential immunomodulating activity.		S1P Receptor , LPL Receptor
T36395	Trotabresib	CC-90010	Epigenetic Reader Domain
	Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.		Epigenetic Reader Domain
T6032	Birabresib	OTX-015,OTX015 （MK 8628/Birabresib）,MK-8628	Epigenetic Reader Domain
	Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4 with potential antineoplastic activity.		Epigenetic Reader Domain
T26778L	Besipirdine hydrochloride	HP 749 hydrochloride,Besipirdine hydrochloride（119257-34-0 Free base)	Adrenergic Receptor
	Besipirdine hydrochloride is a non-receptor-dependent cholinomimetic compound with alpha-adrenergic and cardiovascular activities.Besipirdine hydrochloride inhibits voltage-dependent sodium-potassium channels and inhibit...		Adrenergic Receptor
T7882	Indomethacin farnesil	Infree	Others , COX , Autophagy
	Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD).		Others , COX , Autophagy
T4507	Chlorphenesin	Adermykon,Chlorophenesin,Gecophen	Antibacterial , Antifungal , Histamine Receptor
	Chlorphenesin (Chlorophenesin) is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release. It is also used as an antimycotic agent.		Antibacterial , Antifungal , Histamine Receptor
T5832	Besifovir		HBV
	Besifovir, a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV).		HBV
T7780	Blarcamesine	AE-37,AVex-73	AChR
	Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.		AChR
T7766	Remdesivir	GS-5734	SARS-CoV , DNA/RNA Synthesis
	Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of viruses. Remdesivir is active against Ebola, SARS, and MERS viru...		SARS-CoV , DNA/RNA Synthesis
T6875	Lesinurad	RDEA594	OAT
	Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with seru...		OAT
T16474	Petesicatib		Cysteine Protease
	Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.		Cysteine Protease
T6964	Resiquimod	R848,S28463	HCV Protease , TLR
	Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti...		HCV Protease , TLR
T8386	Esomeprazole Magnesium trihydrate	(S)-Omeprazole magnesium trihydrate	Proton pump
	Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit...		Proton pump
T40864	Magnesium sulfate		Others
	Magnesium sulfate is the preferred anticonvulsant for preventing and controlling eclamptic seizures. Additionally, it is extensively utilized as a tocolytic agent.		Others
TP2219L	Alytesin acetate		Others
	Alytesin acetate is an amphibian bombesin-like peptide.		Others
T67822L	Ulodesine	BCX4208	Endogenous Metabolite
	Ulodesine (BCX4208) is a purine nucleoside phosphorylase (PNP) inhibitor that inhibits PNP with an IC50 value of 2.293 nM/L. Ulodesine may be used to study hyperuricaemia.		Endogenous Metabolite
T8391	Cesium chloride	CsCl	Potassium Channel
	Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.		Potassium Channel
T67817	Besifovir PM	LB80331 PM	HBV
	Besifovir PM (LB80331 PM) is an analogue of Besifovir, a novel orally available acyclic nucleotide phosphonate for the treatment of chronic hepatitis B infection.		HBV
TP1153L	Fibronectin Adhesion-promoting Peptide acetate	Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate	Others
	Fibronectin Adhesion-promoting Peptide acetate (Heparin Binding Peptide acetate) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.		Others
TP1916L1	[D-Phe12,Leu14]-Bombesin acetate	[D-Phe12,Leu14]-Bombesin acetate(108437-88-3 Free base)	Bombesin Receptor
	[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.		Bombesin Receptor
T3712	Mivebresib	ABBV-075	Apoptosis , Epigenetic Reader Domain
	Mivebresib (ABBV-075), also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing protein) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the...		Apoptosis , Epigenetic Reader Domain
T0991	Desipramine hydrochloride	NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
	Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt...
T3272	Metamizole magnesium	Metamizolemagnesiumsalt	Antibiotic
	Metamizole magnesium (Metamizolemagnesiumsalt) is a pain reliever, which can antispasmodic.		Antibiotic
T9978	Glutathione synthesis-IN-1		Others
	Glutathione synthesis-IN-1 (DC-1) is a inhibitor of glutathione synthesis[1].		Others
TP2239L	[D-Phe12]-Bombesin acetate	[D-Phe12]-Bombesin acetate(108437-87-2 free base)	Bombesin Receptor
	[D-Phe12]-Bombesin acetate inhibits bombesin-stimulated secretion.		Bombesin Receptor
T3597	Cutamesine dihydrochloride	AGY94806 dihydrochloride,SA4503 (dihydrochloride),SA4503 dihydrochloride	Sigma receptor
	Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitr...		Sigma receptor
T0015	Mephenesin	Cresoxydiol,Memphenesin,Mephedan,Decontractyl	NMDAR , iGluR
	Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.		NMDAR , iGluR
T1418	Bucladesine sodium	dbcAMP,Dibutyryl-cAMP sodium salt,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt	PKA , PDE
	Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-in...		PKA , PDE
T1885	Siramesine hydrochloride	Lu 28-179 hydrochloride	Ferroptosis , Sigma receptor , lysosomal autophagy
	Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent anticancer activity in vivo.		Ferroptosis , Sigma receptor , lysosomal autophagy
T2686	Esomeprazole Magnesium	(S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium	ATPase , Proton pump
	Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block...		ATPase , Proton pump
T4111	Blarcamesine hydrochloride	Anavex 2-73,AVex-73 hydrochloride,AE-37 hydrochloride	Sigma receptor
	Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).		Sigma receptor
T9379	L-Threonic acid magnesium salt		Others
	L-Threonic acid magnesium salt (L-TAMS) increases synapse density and memory ability in both aged rats and late stage Alzheimer’s disease (AD) model mice.		Others
TP1281L1	Bombesin acetate(31362-50-2 free base)		Bombesin Receptor
	Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina). It has two known homologs in mammals called neuromedin B and gastrin-releasing peptide.		Bombesin Receptor
T8495	Alobresib	Vorolanib,GS-5829	Epigenetic Reader Domain
	Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.		Epigenetic Reader Domain
T5939	Calcium dobesilate		Apoptosis , Others
	Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.		Apoptosis , Others
T6406	Besifloxacin Hydrochloride	BOL-303224-A,Besivance hydrochloride,Besifloxacin HCl	Antibacterial , Antibiotic
	Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.		Antibacterial , Antibiotic
T65281	Magnesium acetate tetrahydrate		Endogenous Metabolite , Antibacterial
	Magnesium acetate tetrahydrate is the hydrated form of the anhydrous magnesium acetate salt.Magnesium acetate tetrahydrate is commonly used to synthesize other compounds, cocoa as an electrolyte supplement or as a reagen...		Endogenous Metabolite , Antibacterial
TQ0318	Filanesib	ARRY-520,ARRY 520	KSP
	Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.		KSP

Compounds

Target: cAMP, Virus Protease

Target: Complement System

Peldesine

T12399

Synonym: BCX 34

Target: Nucleoside Antimetabolite/Analog, HIV Protease

Besipirdine

T26778

Synonym: HP 749 free base,P-867493,P867493,HP 749,HP749,P 867493

Target: Sodium Channel, Adrenergic Receptor

Sovilnesib

T39994

Synonym: AMG650

Target: Microtubule Associated

L-Ascorbic acid 2-phosphate magnesium

T19389

Synonym: 2-Phospho-L-ascorbic acid magnesium

Target: Phosphatase, Phosphorylase

Galidesivir

T10491

Synonym: BCX4430,Immucillin-A

Target: Others

Magnesium glycinate

T4512

Synonym: magnesium 2-aminoacetate,Magnesium diglycinate

Target: Others

Saroglitazar Magnesium

Synonym: Talion,TAU 284,Bepreve,Bepotastine Beslilate

Target: Histamine Receptor

Ponesimod

T3258

Synonym: ACT-128800

Target: S1P Receptor, LPL Receptor

Trotabresib

T36395

Synonym: CC-90010

Target: Epigenetic Reader Domain

Birabresib

T6032

Synonym: OTX-015,OTX015 （MK 8628/Birabresib）,MK-8628

Target: Epigenetic Reader Domain

Besipirdine hydrochloride

T26778L

Synonym: HP 749 hydrochloride,Besipirdine hydrochloride（119257-34-0 Free base)

Target: Adrenergic Receptor

Indomethacin farnesil

T7882

Synonym: Infree

Target: Others, COX, Autophagy

Chlorphenesin

T4507

Synonym: Adermykon,Chlorophenesin,Gecophen

Target: Antibacterial, Antifungal, Histamine Receptor

Synonym: AE-37,AVex-73

Target: SARS-CoV, DNA/RNA Synthesis

Target: Cysteine Protease

Resiquimod

T6964

Synonym: R848,S28463

Target: HCV Protease, TLR

Esomeprazole Magnesium trihydrate

T8386

Synonym: (S)-Omeprazole magnesium trihydrate

Target: Endogenous Metabolite

Cesium chloride

T8391

Synonym: CsCl

Target: Potassium Channel

Fibronectin Adhesion-promoting Peptide acetate

TP1153L

Synonym: Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate

Target: Others

[D-Phe12,Leu14]-Bombesin acetate

TP1916L1

Synonym: [D-Phe12,Leu14]-Bombesin acetate(108437-88-3 Free base)

Target: Bombesin Receptor

Mivebresib

T3712

Synonym: ABBV-075

Target: Apoptosis, Epigenetic Reader Domain

Desipramine hydrochloride

T0991

Synonym: NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor

Metamizole magnesium

T3272

Synonym: Metamizolemagnesiumsalt

Target: Antibiotic

Glutathione synthesis-IN-1

T9978

Synonym:

Target: Others

[D-Phe12]-Bombesin acetate

TP2239L

Synonym: [D-Phe12]-Bombesin acetate(108437-87-2 free base)

Target: Bombesin Receptor

Cutamesine dihydrochloride

T3597

Synonym: AGY94806 dihydrochloride,SA4503 (dihydrochloride),SA4503 dihydrochloride

Target: Sigma receptor

Mephenesin

T0015

Synonym: Cresoxydiol,Memphenesin,Mephedan,Decontractyl

Target: NMDAR, iGluR

Bucladesine sodium

T1418

Synonym: dbcAMP,Dibutyryl-cAMP sodium salt,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt

Target: PKA, PDE

Siramesine hydrochloride

T1885

Synonym: Lu 28-179 hydrochloride

Target: Ferroptosis, Sigma receptor, lysosomal autophagy

Esomeprazole Magnesium

T2686

Synonym: (S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium

Target: ATPase, Proton pump

Blarcamesine hydrochloride

T4111

Synonym: Anavex 2-73,AVex-73 hydrochloride,AE-37 hydrochloride

Target: Sigma receptor

L-Threonic acid magnesium salt

T9379

Synonym:

Target: Others

Bombesin acetate(31362-50-2 free base)

TP1281L1

Synonym:

Target: Bombesin Receptor

Alobresib

T8495

Synonym: Vorolanib,GS-5829

Target: Epigenetic Reader Domain

Calcium dobesilate

T5939

Synonym:

Target: Apoptosis, Others

Besifloxacin Hydrochloride

T6406

Synonym: BOL-303224-A,Besivance hydrochloride,Besifloxacin HCl

Target: Antibacterial, Antibiotic

Magnesium acetate tetrahydrate

T65281

Synonym:

Target: Endogenous Metabolite, Antibacterial

Filanesib

TQ0318

Synonym: ARRY-520,ARRY 520

Target: KSP

Cat No.	Product Name	Synonyms	Targets
T9425	Epipinoresinol-4'-O-β-D-glucoside		Others
	Epipinoresinol-4'-O-β-D-glucoside (Simplocosin) is a glucoside compound[1].		Others
TN1594	DL-Syringaresinol	(±)-Syringaresinol	Antioxidant , Antifungal
	DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin agi...		Antioxidant , Antifungal
T2S0531	Pinoresinol dimethyl ether	(+)-Eudesmin	Others , PKC
	Pinoresinol dimethyl ether, a non-phenolic furan lignan isolated from the bark of Magnolia kobus, exhibits neuroactivity. It stimulates upstream MAPK, PKC, and PKA pathways, inducing neurite outgrowth in PC12 cells.		Others , PKC
TN1853	Lariciresinol		VEGFR , Antifection
	Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel antifungal agent for the treatment of fungal infectious disease...		VEGFR , Antifection
T22455	Vindesine sulfate	DVA,Desacetylvinblastine amide,DAVA,Desacetyl Vinblastine amide,VDS	Others
	Vindesine sulfate (Desacetyl Vinblastine amide) is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule...		Others
T5755	Aloesin		Tyrosinase
	Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin.		Tyrosinase
T13739	Isopropylidenylacetyl-marmesin	(±)-Prantschimgin,Prantschimgin	Others
	Isopropylidenylacetyl-marmesin (Prantschimgin) is a natural product derived from the roots of Notopterygium incisum and Ferulago bracteata.		Others
T3S0488	Syringaresinol diglucoside	Syringaresinol-di-O-glucoside	Others
	Syringaresinol diglucoside (Syringaresinol-di-O-glucoside) protects the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memory, and the st...		Others
TN2079	(-)-Pinoresinol		Others , TNF , NF-κB , COX
	(-)-Pinoresinol is isolated from the whole plant of Serissa japonica (Thunb.) Thunb.		Others , TNF , NF-κB , COX
T4S0792	Pinoresinol 4-O-β-D-glucopyranoside	(+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside	Others
	(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia. It exhibits antioxidative, antihypertensive activities, and acts as an inhibitor of cyclic adenosine monophosp...		Others
TN1782	(+)-Isolariciresinol	(+)-Cyclolariciresinol,Isolariciresinol	Immunology/Inflammation related
	(+)-Isolariciresinol ((+)-Cyclolariciresinol) is extracted from Radix Isatidis and shows antioxidant and anti-inflammatory activities and can be used in studies about rheumatism.		Immunology/Inflammation related
T4A2458	Resibufogenin	Bufogenin,Recibufogenin	Others
	1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff...		Others
T0739	Guaifenesin	Glycerol guaiacolate,Guaiacol glyceryl ether,Guaiphenesin	Others
	Guaifenesin (Guaiphenesin) is an expectorant that also has some muscle relaxing action. It is used in many cough preparations.		Others
TJS0487	(-)-Syringaresinol	DL-Syringaresinol,Lirioresinol b	Others
	(-)-Syringaresinol (DL-Syringaresinol) is derived from the stems of Annona Montana. (-)-Syringaresinol inhibits the proliferation of human promyelocytic HL-60 cells through G1 arrest and induction of apoptosis and posses...		Others
T5759	S-(+)-Marmesin	(+)-Marmesin,(S)-Marmesin,marmesin	Lipoxygenase , COX
	S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.		Lipoxygenase , COX
T8179	Aloeresin D		Beta-Secretase , BACE
	Aloeresin D, a natural chromone glycoside, inhibits β-Secretase (BACE1) activity (IC50: 39 μM).		Beta-Secretase , BACE
T3S1265	Liriopesides B	Nolinospiroside F	Others
	Liriopesides B (Nolinospiroside F) exhibited potential anticancer activity against human ovarian cancer A2780 cells.		Others
T5S2178	Fargesin	(+/-)-Fargesin	Adrenergic Receptor
	1. Fargesin ((+/-)-Fargesin) as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats. 2. Fargesin improves dyslipidemia and hyperglycemia by activating...		Adrenergic Receptor
TMS0484	Episyringaresinol 4'-O-β-D-glncopyranoside	(-)-Syringaresinol 4-O-β-D-glucopyranosi	Others
	Episyringaresinol 4'-O-β-D-glncopyranoside ((-)-Syringaresinol 4-O-β-D-glucopyranosi) inhibits the proliferation of human promyelocytic HL-6 cells through G(1) arrest and induction of apoptosis, may be a potential chemot...		Others
TN2080	Pinoresinol	(+)-Pinoresinol	Apoptosis , NF-κB , CDK , p53
	Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st...		Apoptosis , NF-κB , CDK , p53
T21820	Resistomycin	Geliomycin,Heliomycin	Antibiotic
	Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis.		Antibiotic
T19281L	Dihydroxyacetone phosphate hemimagnesium hydrate	DHAP Mg,Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base)	Others
	Dihydroxyacetone phosphate hemimagnesium salt hydrate is also known as dihydroxyacetone phosphate or 3-hydroxy-2-oxopropyl phosphate. Dihydroxyacetone phosphate hemimagnesium salt hydrate is found in all organisms from b...		Others
TN1916	Matairesinol		ATPase , p38 MAPK , ROS
	Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducible factor-1α± in hypoxic HeLa cells.		ATPase , p38 MAPK , ROS
TP2223	Beesioside Q		Others
	Beesioside Q is a natural product extracted from the rhizome of Beesia calthaefolia (Maxim.) Ulbr.		Others
T3415	Secoisolariciresinol diglucoside	LGM2605	ROS
	Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ...		ROS
T6S0535	Pinoresinol diglucoside	Pinoresinol Diglucopyranoside	Glucosidase
	1. Pinoresinol diglucoside (Pinoresinol Diglucopyranoside) is a putative α-glucosidase inhibiting compound. 2. Pinoresinol diglucoside is a important antihypertensive compound.		Glucosidase
TN2197	Secoisolariciresinol		TNF
	Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes.		TNF
T20793	Magnesium Lithospermate B	Monomethyl lithospermate B,Lithospermate B	Others
	Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is...		Others
TN4510	(+)-Medioresinol Di-O-β-D-glucopyranoside	(+)-Mediresinol Di-O-beta-D-glucopyranoside,(+)-Medioresinol Di-O-β-D-glucopyranoside	PDE
	(+)-Medioresinol Di-O-β-D-glucopyranoside has strong inhibitory activity of cyclic AMP phosphodiesterase.		PDE
T8772	Sumaresinolic Acid		Others
	Sumaresinolic Acid is a natural lignan found in a variety of plants such as flaxseed, sesame and wheat bran and is a secondary metabolite of plants. It has been widely studied for its potential health benefits, including...		Others
TN5015	Siaresinolic acid 28-O-β-D-glucopyranosyl ester	Siaresinolic acid 28-O-beta-D-glucopyranosyl ester	Others
	Siaresinolic acid 28-O-β-D-glucopyranosyl ester is a natural product for research related to life sciences. The catalog number is TN5015 and the CAS number is 155653-86-4.		Others
TN5402	(-)-Pinoresinol 4-O-glucoside
	(-)-Pinoresinol 4-O-glucoside is a natural product from Lonicera japonica THUNB.
TN3127	5'-Methoxylariciresinol		Others
	5'-Methoxylariciresinol is a natural product from Stellera chamaejasme.		Others
TN3077	5,5'-Dimethoxylariciresinol 4-O-glucoside		Others
	5,5'-Dimethoxylariciresinol-4'-O-beta-D-glucoside is shown to effectively enhance chemosensitivity of resistant cells, which makes it may be a suitable candidate for potential multidrug resistance (MDR)-reversing agents.		Others
TMA0627	Taxiresinol		TNF
	Taxiresinol shows anticancer, antinociceptive, and antiallergic activities, it shows inhibitory activity on induced histamine release from the human basophilic cell line, KU812. Taxiresinol can protect the hepatocytes fr...		TNF
TN3355	Agatharesinol acetonide		Antifection
	Agatharesinol acetonide shows anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM).		Antifection
TN4333	Isotaxiresinol 9,9'-acetonide		Others
	Isotaxiresinol 9,9'-acetonide is a natural product for research related to life sciences. The catalog number is TN4333 and the CAS number is 252333-72-5.		Others
TN3334	Abiesinol F		Others
	Abiesinol F is a natural product for research related to life sciences. The catalog number is TN3334 and the CAS number is 1190070-91-7.		Others
TN3310	9,9'-Di-O-(E)-feruloylsecoisolariciresinol		mTOR
	1,4-O-Diferuloylsecoisolariciresinol(9,9'-Di-O-(E)-feruloylsecoisolariciresinol),and pierreione B, two novel inhibitors of mTOR signaling, have strong anticancer activity. (+)-9,9'-O-Diferuloylsecoisolariciresinol has si...		mTOR
TN1392	Anhydrosecoisolariciresinol		Others
	Anhydrosecoisolariciresinol can significantly decrease the growth of human breast cancer MCF-7 and MDA-MB-231 cell lines at 50 and 100 microM.		Others
TN6160	Pleionesin C
	Pleionesin C is a natural product for research related to life sciences. The catalog number is TN6160 and the CAS number is 1222077-25-9.
TN2299	Vindesine		Others
	Vindesine is a microtubule inhibitor and widely used to treat malignancies. Vindesine neuropathy seems to be the cause of the patient's neurological symptoms.		Others
TN4507	Matairesinoside		Others
	Matairesinoside is a natural product from Styrax japonica.		Others
TN2545	1-Hydroxypinoresinol 1-O-glucoside		ROS
	(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 +/- 0.04, 2.26 +/- 0.07 and 32.3 +/- 0.13 microM, respectively.		ROS
TN3286	8-Hydroxypinoresinol diglucoside		Others
	8-Hydroxypinoresinol diglucoside is a natural product for research related to life sciences. The catalog number is TN3286 and the CAS number is 112747-99-6.		Others
TN3900	Ducheside A		Others
	Ducheside A is a natural product from Diplopanax stachyanthus.		Others
TN1900	(-)-Lyoniresinol		Others
	(-)-Lyoniresinol has antioxidant activity.		Others
T83252	7′-Methoxylariciresinol
	7′-Methoxylariciresinol, a phenylpropanoid, can be isolated from Crataegus pinnatifida [1].
T82522	Dugesin C
	Dugesin C, a diterpenoid extracted from Salvia dugesii, showcases a spiro carbocyclic ring system originating from the standard neocrotane skeleton [1].
T82523	Dugesin B	(-)-Isosalvipuberulin,(-)-Isopuberulin
	Dugesin B ((-)-Isosalvipuberulin) is a rearranged clerodane diterpenoid isolated from the aerial parts of Salvia dugesii [1].
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Natural Products

Epipinoresinol-4'-O-β-D-glucoside

Synonym: (±)-Syringaresinol

Target: Antioxidant, Antifungal

Pinoresinol dimethyl ether

T2S0531

Synonym: (+)-Eudesmin

Target: VEGFR, Antifection

Vindesine sulfate

T22455

Synonym: DVA,Desacetylvinblastine amide,DAVA,Desacetyl Vinblastine amide,VDS

Isopropylidenylacetyl-marmesin

T13739

Synonym: (±)-Prantschimgin,Prantschimgin

Target: Others

Syringaresinol diglucoside

T3S0488

Synonym: Syringaresinol-di-O-glucoside

Target: Others, TNF, NF-κB, COX

Pinoresinol 4-O-β-D-glucopyranoside

T4S0792

Synonym: (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside

Target: Others

(+)-Isolariciresinol

TN1782

Synonym: (+)-Cyclolariciresinol,Isolariciresinol

Target: Immunology/Inflammation related

Resibufogenin

T4A2458

Synonym: Bufogenin,Recibufogenin

Target: Others

Guaifenesin

T0739

Synonym: Glycerol guaiacolate,Guaiacol glyceryl ether,Guaiphenesin

Target: Others

(-)-Syringaresinol

TJS0487

Synonym: DL-Syringaresinol,Lirioresinol b

Target: Others

S-(+)-Marmesin

T5759

Synonym: (+)-Marmesin,(S)-Marmesin,marmesin

Target: Lipoxygenase, COX

Aloeresin D

T8179

Synonym:

Target: Beta-Secretase, BACE

Liriopesides B

T3S1265

Synonym: Nolinospiroside F

Target: Others

Fargesin

T5S2178

Synonym: (+/-)-Fargesin

Target: Adrenergic Receptor

Episyringaresinol 4'-O-β-D-glncopyranoside

TMS0484

Synonym: (-)-Syringaresinol 4-O-β-D-glucopyranosi

Target: Others

Pinoresinol

TN2080

Synonym: (+)-Pinoresinol

Target: Apoptosis, NF-κB, CDK, p53

Resistomycin

T21820

Synonym: Geliomycin,Heliomycin

Target: Antibiotic

Dihydroxyacetone phosphate hemimagnesium hydrate

T19281L

Synonym: DHAP Mg,Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base)

Target: ATPase, p38 MAPK, ROS

Secoisolariciresinol diglucoside

T3415

Synonym: LGM2605

Target: ROS

Pinoresinol diglucoside

T6S0535

Synonym: Pinoresinol Diglucopyranoside

Magnesium Lithospermate B

T20793

Synonym: Monomethyl lithospermate B,Lithospermate B

Target: Others

(+)-Medioresinol Di-O-β-D-glucopyranoside

TN4510

Synonym: (+)-Mediresinol Di-O-beta-D-glucopyranoside,(+)-Medioresinol Di-O-β-D-glucopyranoside

Siaresinolic acid 28-O-β-D-glucopyranosyl ester

TN5015

Synonym: Siaresinolic acid 28-O-beta-D-glucopyranosyl ester

Target: Others

(-)-Pinoresinol 4-O-glucoside

TN5402

Synonym:

Target:

5'-Methoxylariciresinol

TN3127

Synonym:

Target: Others

5,5'-Dimethoxylariciresinol 4-O-glucoside

Agatharesinol acetonide

TN3355

Synonym:

Target: Antifection

Isotaxiresinol 9,9'-acetonide

9,9'-Di-O-(E)-feruloylsecoisolariciresinol

TN3310

Synonym:

Target: mTOR

Anhydrosecoisolariciresinol

1-Hydroxypinoresinol 1-O-glucoside

TN2545

Synonym:

Target: ROS

8-Hydroxypinoresinol diglucoside

7′-Methoxylariciresinol

Synonym: (-)-Isosalvipuberulin,(-)-Isopuberulin

Target:

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01909	Elafin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein ...
TMPH-03031	P30 adhesin Protein, Mycoplasma pneumoniae, Recombinant (GST & His)	Mycoplasma pneumoniae	E. coli
	Adhesin necessary for successful cytadherence and virulence. P30 adhesin Protein, Mycoplasma pneumoniae, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular wei...
TMPY-02660	Resistin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Resistin is an adipocytokine, which has been studied for its role in insulin resistance and recently in inflammation. The RETN and CAP1 polymorphisms and gene expression may be potential biomarkers for breast cancer risk...
TMPH-03144	SEY1 Protein, Plasmodium knowlesi, Recombinant (His)	Plasmodium knowlesi	E. coli
	Probable GTP-binding protein that may be involved in cell development. SEY1 Protein, Plasmodium knowlesi, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 1...
TMPY-01127	Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA Protein (His)	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is A8HWY8.
TMPH-00298	Resistin Protein, Bovine, Recombinant (His)	Bovine	E. coli
	Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Resistin Protein, Bovine, Recombinant (His) is expressed in E. coli expression system ...
TMPY-04305	Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA Protein (R339G & S341R, His)	H5N1	Baculovirus Insect Cells
	Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA Protein (R339G & S341R, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60 kDa and the accession number is A8HWY8.
TMPJ-00014	Resistin Protein, Human, Recombinant (His)	Human	E. coli
	Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into ...
TMPY-02847	Moesin Protein, Human, Recombinant (aa 1-346, His)	Human	E. coli
	Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins, highly related members of the larger protein 4.1 superfamily, can exist in an active or inactive conformation. It seems that ERM protei...
TMPY-04589	Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA-specific B cell probe Protein (His)	H5N1	Baculovirus Insect Cells
	Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA-specific B cell probe Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.2 kDa and the accession number is AHJ...
TMPH-00508	Pro-resilin Protein, Drosophila melanogaster, Recombinant (His & Myc)	Fruit fly	E. coli
	Plays a central role in insect flight by providing low stiffness, high strain and efficient energy storage.

Elafin Protein, Human, Recombinant (His)

TMPY-01909

Species: Human

Expression System: HEK293 Cells

P30 adhesin Protein, Mycoplasma pneumoniae, Recombinant (GST & His)

TMPH-03031

Species: Mycoplasma pneumoniae

Expression System: E. coli

Resistin Protein, Mouse, Recombinant (hFc)

TMPY-02660

Species: Mouse

Expression System: HEK293 Cells

SEY1 Protein, Plasmodium knowlesi, Recombinant (His)

TMPH-03144

Species: Plasmodium knowlesi

Expression System: E. coli

Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA Protein (His)

TMPY-01127

Species: H5N1

Expression System: HEK293 Cells

Resistin Protein, Bovine, Recombinant (His)

TMPH-00298

Species: Bovine

Expression System: E. coli

Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA Protein (R339G & S341R, His)

TMPY-04305

Species: H5N1

Expression System: Baculovirus Insect Cells

Resistin Protein, Human, Recombinant (His)

TMPJ-00014

Species: Human

Expression System: E. coli

Moesin Protein, Human, Recombinant (aa 1-346, His)

TMPY-02847

Species: Human

Expression System: E. coli

Influenza A H5N1 (A/Indonesia/5/2005) Hemagglutinin/HA-specific B cell probe Protein (His)

TMPY-04589

Species: H5N1

Expression System: Baculovirus Insect Cells

Pro-resilin Protein, Drosophila melanogaster, Recombinant (His & Myc)

TMPH-00508

Species: Fruit fly

Expression System: E. coli

Cat No.	Product Name
L7900	Osteogenesis Compound Library	317 compounds
	A unique collection of 317 osteogenesis related compounds for high throughput and high content screening;
L4800	Angiogenesis related Compound Library	1353 compounds
	A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L7100	Anti-Obesity Compound Library	2247 compounds
	A unique collection of 2247 anti-obesity compounds for high throughput and high content screening;

Libraries

Osteogenesis Compound Library

L7900

Compounds: 317

Angiogenesis related Compound Library

L4800

Compounds: 1353

Anti-Obesity Compound Library

L7100

Compounds: 2247