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Anti-FOXD3 Monoclonal Antibody (2L13)

(Synonyms: HFH2, Genesis, FOXD3, AIS1) Copy Product Info
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Synonyms: HFH2, Genesis, FOXD3, AIS1

Catalog No. TMAT-1621 Copy Product Info
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Anti-FOXD3 Monoclonal Antibody (2L13) is a Mouse antibody targeting FOXD3. Anti-FOXD3 Monoclonal Antibody (2L13) can be used in WB,IHC.

Anti-FOXD3 Monoclonal Antibody
(2L13)

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Product Introduction

Bioactivity
Description
Anti-FOXD3 Monoclonal Antibody (2L13) is a Mouse antibody targeting FOXD3. Anti-FOXD3 Monoclonal Antibody (2L13) can be used in WB,IHC.
SynonymsHFH2, Genesis, FOXD3, AIS1
Ig Type
IgG1
Clone
2L13
Reactivity
Human,Mouse,Monkey
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide.
Concentration1 mg/mL
Research BackgroundFoxD3 is a member of the Forkhead Box family and is characterized by a winged-helix DNA-binding structure and the important role it plays in embryonic development . This transcriptional regulator is required for the maintenance of pluripotency in the pre-implantation and peri-implantation stages of mouse embryonic development and is also required for trophoblast formation. FoxD3 is required for the maintenance of the mammalian neural crest; FoxD3(-/-) mouse embryos fail around the time of implantation with loss of neural crest-derived structures. FoxD3 also forms a regulatory network with Oct-4 and NANOG to maintain the pluripotency of ES cells. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. Tissue specificity: Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human FOXD3 expressed in E. Coli.
Antigen Species
Human
Gene Name
FOXD3
Gene ID
Protein Name
Forkhead box protein D3
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 50 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-FOXD3 Monoclonal Antibody (2L13) molecular weight