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(S,S)-Secoisolariciresinol diglucoside
🥰Excellent
Catalog No. TN5418Cas No. 257930-74-8
Alias Secoisolariciresinol diglucoside, (S,S)-SDG
(S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis.
(S,S)-Secoisolariciresinol diglucoside
🥰Excellent
Purity: 99.33%
Catalog No. TN5418Alias Secoisolariciresinol diglucoside, (S,S)-SDGCas No. 257930-74-8
(S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $51 | - | In Stock | |
| 5 mg | $81 | - | In Stock | |
| 10 mg | $140 | - | In Stock | |
| 25 mg | $269 | - | In Stock | |
| 50 mg | $383 | - | In Stock | |
| 100 mg | $655 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.33%
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Product Introduction
Bioactivity
Chemical Properties
| Description | (S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis. |
| In vitro | Secoisolariciresinol diglucoside is a major lignan component in flaxseed and exhibits potent antioxidant activity in vitro, acting as an effective scavenger of free hydroxyl radicals[1]. |
| In vivo | Secoisolariciresinol diglucoside (oral administration; 4 mg/mouse) administered to 10-week-old male mice 2 hours before the administration of tumor necrosis factor alpha (TNFα) significantly reduced the adhesion of leukocytes to the endothelium by 50% and the migration of leukocytes across the blood-brain barrier by 64%[2]. |
| Synonyms | Secoisolariciresinol diglucoside, (S,S)-SDG |
| Molecular Weight | 686.7 |
| Formula | C32H46O16 |
| Cas No. | 257930-74-8 |
| Smiles | [C@@H]([C@H](CC1=CC(OC)=C(O)C=C1)CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)(CC3=CC(OC)=C(O)C=C3)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O |
| Relative Density. | 1.52 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 80 mg/mL (116.50 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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