an 9

Pivanex (Pivalyloxymethyl butyrate) is an orally active HDAC inhibitor and an antimetastatic and antiangiogenic agent. Pivanex downregulates the Bcr-Abl protein and enhances apoptosis.

7-Phenyl-6-azaspiro[4.5]Decan-9-ol, with CAS No. 301320-54-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Phenyl-6-azaspiro[4.5]Decan-9-ol provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Heptadecan-9-yl 8-(3-hydroxypropylamino)octanoate is a lipid with a propanolamine headgroup, an octanoate ester, and a branched C17 tail.

Heptadecan-9-yl 6-bromohexanoate is a chemical reagent characterized by a bromide attached to a relatively large ester chain, composed of a C6 ester coupled with the central position of a C17 chain. The bromide is readily replaced by nucleophiles in substitution reactions. Heptadecan-9-yl 6-bromohexanoate can serve as an intermediate for constructing lipid nanoparticles.

Heptadecan-9-yl 10-bromodecanoate is an intermediate in the synthesis of lipid molecules.

Acridan-9-carboxylic acid, 10-methyl-, 2-(diethylamino)ethyl ester, hydrochloride is a biochemical.

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6'-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione is a useful organic compound for research related to life sciences. The catalog number is T67236 and the CAS number is 1352957-59-5.

(1'R,3a'R,8a'S,9'S,9a'S)-1'-Methyl-3'-oxo-N,N-diphenyl-3',3a',5',7',8',8a',9',9a'-octahydro-1'H-spiro[[1,3]dioxolane-2,6'-naphtho[2,3-c]furan]-9'-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67324 and the CAS number is 900160-98-7.

Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate is employed in lipid nanoparticle (LNP) delivery systems for mRNA vaccine delivery [1].

Heptadecan-9-yl 8-bromooctanoate is a chemical compound that can be utilized in the construction or modification of lipid nanoparticles.

Heptadecan-9-yl 8-((2-hydroxyethyl)amino)octanoate is a lipid utilized in compound synthesis.

M9 glycan (Man9), 2-AA labelled (Mannose-9 N-linked oligosaccharide, 2-AA labelled; Oligomannose 9 glycan, 2-AA labelled) is a polymeric N-glycoprotein that serves as a versatile fluorescent linker. The resulting conjugate exhibits high sensitivity and specificity by mimicking the antenna elements of N-glycans.

M9 glycan (Man9) (Mannose-9 N-linked oligosaccharide; Oligomannose 9 glycan) is a polymeric N-glycoprotein that serves as a versatile fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antenna elements of N-glycans.

M9 glycan (Man9), 2-AB labelled (Mannose-9 N-linked oligosaccharide, 2-AB labelled; Oligomannose 9 glycan, 2-AB labelled), is a polymeric N-glycoprotein that serves as a versatile fluorescent linker. The resulting conjugates mimic the antenna elements of N-glycans, offering high sensitivity and specificity.

M9 glycan (Man9), procainamide labelled (Mannose-9 N-linked oligosaccharide, procainamide labelled; Oligomannose 9 glycan, procainamide labelled) is a type of poly N-glycoprotein and serves as a versatile fluorescent linker. The resulting conjugates possess high sensitivity and specificity by mimicking the antennae elements of N-glycans.

Heptadecan-9-ol (9-Heptadecanol) is a lipid characterized by a secondary hydroxyl group and two nonpolar tails.

Heptadecan-9-amine (9-Aminoheptadecane) is a PEG linker featuring maleimide and TFP ester terminal groups. The maleimide group reacts with thiols at a pH between 6.5 and 7.5, while the TFP ester can interact with primary amine groups and is less susceptible to hydrolysis than NHS esters. The hydrophilic PEG chain enhances the compound's solubility in aqueous media, with longer PEG chains offering improved solubility compared to shorter ones.

(R)-2-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetonitrile is a pharmaceutical intermediate employed in the synthesis of various active compounds.

C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM.

MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).

9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling molecules.

RIPK1-IN-9 is a potent and selective inhibitor of RIPK1, a dihydronaphthone compound, which inhibits U937 and L929 cells with an IC50 of 2 nM and 1.3 nM, respectively.

TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.

SARS-CoV-2 Mpro-IN-9 (compound c7), a nonpeptidic, noncovalent inhibitor of SARS-CoV-2 main protease (Mpro), exhibits potent inhibitory action (IC50 = 0.085 μM) and improved physicochemical and drug metabolism and pharmacokinetics (DMPK) properties. It effectively suppresses viral replication in SARS-CoV-2-infected Vero E6 cells (EC50 = 1.10 μM) and demonstrates low cytotoxicity (CC50 > 50 μM) [1].