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Anti-CD59 Antibody (9I973) (Synonyms: CD59 molecule, CD59)

Catalog No. TMAY-03807 Copy Product Info
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Anti-CD59 Antibody (9I973) is a Rabbit antibody targeting CD59. Anti-CD59 Antibody (9I973) can be used in ELISA.

Anti-CD59 Antibody (9I973)

Copy Product Info
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Catalog No. TMAY-03807
Synonyms CD59 molecule, CD59

Anti-CD59 Antibody (9I973) is a Rabbit antibody targeting CD59. Anti-CD59 Antibody (9I973) can be used in ELISA.

Anti-CD59 Antibody
(9I973)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2687-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD59 Antibody (9I973) is a Rabbit antibody targeting CD59. Anti-CD59 Antibody (9I973) can be used in ELISA.
SynonymsCD59 molecule, CD59
Ig Type
Rabbit IgG
Clone
9I973
Reactivity
Rat
Specificity
Rat CD59
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Rat CD59 (rR CD59; TMPY-03091; P27274; Met1-Asn100).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Rat CD59 Protein (TMPY-03091)
Antigen Species
Rat
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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