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Anti-CDNF Antibody (9D614)
😃Good
Catalog No. TMAY-02801
Alias cerebral dopamine neurotrophic factor, Armetl1, 9330140G23
Anti-CDNF Antibody (9D614) is a Mouse antibody targeting CDNF. Anti-CDNF Antibody (9D614) can be used in ELISA.
Anti-CDNF Antibody (9D614)
Anti-CDNF Antibody (9D614)
😃Good
Catalog No. TMAY-02801Alias cerebral dopamine neurotrophic factor, Armetl1, 9330140G23
Anti-CDNF Antibody (9D614) is a Mouse antibody targeting CDNF. Anti-CDNF Antibody (9D614) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Chemical Properties
| Description | Anti-CDNF Antibody (9D614) is a Mouse antibody targeting CDNF. Anti-CDNF Antibody (9D614) can be used in ELISA. |
| Alias | cerebral dopamine neurotrophic factor, Armetl1, 9330140G23 |
| Ig Type | Monoclonal Mouse IgG2b |
| Clone | 9D614 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CDNF / ARMETL1 (rh CDNF / ARMETL1; TMPY-00568; NP_001025125.2; Met1-Leu187). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionarily conserved protein family. CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor (GDNF). CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease, suggesting that CDNF might be beneficial for the treatment of Parkinson's disease. CDNF is widely expressed in neurons in several brain regions including cerebral cortex, hippocampus, substantia nigra, striatum and cerebellum. Human CDNF is glycosylated and secreted from transiently transfected cells. CDNF promotes the survival, growth, and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CDNF / ARMETL1 Protein (TMPY-00568) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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