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Anti-OSMR Antibody (9K249) (Synonyms: OSMRB, oncostatin M receptor)
Catalog No. TMAY-01774 Copy Product Info
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Anti-OSMR Antibody (9K249) is a Mouse antibody targeting OSMR. Anti-OSMR Antibody (9K249) can be used in ELISA,ELISA(Det),IP.
Anti-OSMR Antibody (9K249)
Copy Product Info🥰Excellent
Catalog No. TMAY-01774
Synonyms OSMRB, oncostatin M receptor
Anti-OSMR Antibody (9K249) is a Mouse antibody targeting OSMR. Anti-OSMR Antibody (9K249) can be used in ELISA,ELISA(Det),IP.
Anti-OSMR Antibody
(9K249)
(9K249)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $69 | 7-10 days | 7-10 days | |
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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| Description | Anti-OSMR Antibody (9K249) is a Mouse antibody targeting OSMR. Anti-OSMR Antibody (9K249) can be used in ELISA,ELISA(Det),IP. |
| Synonyms | OSMRB, oncostatin M receptor |
| Ig Type | Mouse IgG1 |
| Clone | 9K249 |
| Reactivity | Human |
| Specificity | Human OSMR |
| Verified Activity | OSMR was immunoprecipitated using: -Lane A:0.5 mg Hela Whole Cell Lysate. -2 µL anti-OSMR mouse monoclonal antibody and 60 μg of Immunomagnetic beads Protein G. -Primary antibody: -Anti-OSMR mouse monoclonal antibody, at 1:100 dilution. -Secondary antibody: -Dylight 800-labeled antibody to Mouse IgG (H+L), at 1:7500 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 111 kDa. -Observed band size: 111 kDa |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000; IP: 0.5-2 μL/mg of lysate; ELISA(Det): 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human OSMR / IL31RB (rh OSMR; TMPY-01305; NP_003990.1; Met 1-Met 740). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the type I cytokine receptor family. IL-31RB/OSMR heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in IL-31RB/OSMR have been associated with familial primary localized cutaneous amyloidosis. Defects in IL-31RB/OSMR are the cause of amyloidosis primary localized cutaneous type 1 (PLCA1), also known as familial lichen amyloidosis of familial cutaneous lichen amyloidosis. PLCA1 is hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening (lichenification) that may be exacerbated by chronic scratching and rubbing. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human OSMR protein (TMPY-01305) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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