Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-OSMR Antibody (9K249)

😃Good
Catalog No. TMAY-01774
Alias OSMRB, oncostatin M receptor

Anti-OSMR Antibody (9K249) is a Mouse antibody targeting OSMR. Anti-OSMR Antibody (9K249) can be used in ELISA,ELISA(Det),IP.

Anti-OSMR Antibody (9K249)

Anti-OSMR Antibody (9K249)

😃Good
Catalog No. TMAY-01774Alias OSMRB, oncostatin M receptor
Anti-OSMR Antibody (9K249) is a Mouse antibody targeting OSMR. Anti-OSMR Antibody (9K249) can be used in ELISA,ELISA(Det),IP.
Pack SizePriceAvailabilityQuantity
20 μL$69 7-10 days
100 μL$199 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Antibody Type: Mouse Monoclonal

Application: ELISA, ELISA(Det), IP

Reactivity: Human
AliasOSMRB, oncostatin M receptor
Ig Type
Mouse IgG1
Clone
9K249
Reactivity
Human
Verified Activity
OSMR was immunoprecipitated using:
-Lane A:0.5 mg Hela Whole Cell Lysate.
-2 µL anti-OSMR mouse monoclonal antibody and 60 μg of Immunomagnetic beads Protein G.
-Primary antibody:
-Anti-OSMR mouse monoclonal antibody, at 1:100 dilution.
-Secondary antibody:
-Dylight 800-labeled antibody to Mouse IgG (H+L), at 1:7500 dilution.
-Developed using the odyssey technique.
-Performed under reducing conditions.
-Predicted band size: 111 kDa.
-Observed band size: 111 kDa
Application
ELISA,ELISA(Det),IP
Recommended Dose
ELISA: 1:1000-1:2000; IP: 0.5-2 μL/mg of lysate; ELISA(Det): 1:1000-1:10000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human OSMR / IL31RB (rh OSMR; TMPY-01305; NP_003990.1; Met 1-Met 740). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundOncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the type I cytokine receptor family. IL-31RB/OSMR heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in IL-31RB/OSMR have been associated with familial primary localized cutaneous amyloidosis. Defects in IL-31RB/OSMR are the cause of amyloidosis primary localized cutaneous type 1 (PLCA1), also known as familial lichen amyloidosis of familial cutaneous lichen amyloidosis. PLCA1 is hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening (lichenification) that may be exacerbated by chronic scratching and rubbing. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human OSMR protein (TMPY-01305)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-OSMR Antibody (9K249) | purchase Anti-OSMR Antibody (9K249) | Anti-OSMR Antibody (9K249) cost | order Anti-OSMR Antibody (9K249)