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Anti-CD253 Monoclonal Antibody (9G813)
(Synonyms: TRAIL, TNLG6A, TNFSF10, TL2, Apo-2L, APO2L) Copy Product Info
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Synonyms: TRAIL, TNLG6A, TNFSF10, TL2, Apo-2L, APO2L
Catalog No. TMAT-0343 Copy Product Info
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Anti-CD253 Monoclonal Antibody (9G813) is a Mouse antibody targeting CD253. Anti-CD253 Monoclonal Antibody (9G813) can be used in FCM.
Anti-CD253 Monoclonal Antibody
(9G813)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD253 Monoclonal Antibody (9G813) is a Mouse antibody targeting CD253. Anti-CD253 Monoclonal Antibody (9G813) can be used in FCM. |
| Synonyms | TRAIL, TNLG6A, TNFSF10, TL2, Apo-2L, APO2L |
| Ig Type | IgG1 |
| Clone | 9G813 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD253 (AA: extra 39-281) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TNFSF10 |
| Gene ID | |
| Protein Name | Tumor necrosis factor ligand superfamily member 10 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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