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Anti-PLCG2 Monoclonal Antibody (9F599)
(Synonyms: PLC-IV, PLC-gamma-2, FCAS3, APLAID) Copy Product Info
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Synonyms: PLC-IV, PLC-gamma-2, FCAS3, APLAID
Catalog No. TMAT-0868 Copy Product Info
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Anti-PLCG2 Monoclonal Antibody (9F599) is a Mouse antibody targeting PLCG2. Anti-PLCG2 Monoclonal Antibody (9F599) can be used in WB,IF,FCM.
Anti-PLCG2 Monoclonal Antibody
(9F599)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PLCG2 Monoclonal Antibody (9F599) is a Mouse antibody targeting PLCG2. Anti-PLCG2 Monoclonal Antibody (9F599) can be used in WB,IF,FCM. |
| Synonyms | PLC-IV, PLC-gamma-2, FCAS3, APLAID |
| Ig Type | IgG2b |
| Clone | 9F599 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. |
| Conjucates | Unconjugated |
| Immunogen | Synthesized peptide of human PLCG2 (AA: phospho-Tyrosine 753 of human Phospholipase Cg2(cERDINSLpYDVSRMYV)). |
| Antigen Species | Human |
| Gene Name | PLCG2 |
| Gene ID | |
| Protein Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 148 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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