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Anti-FER Monoclonal Antibody (9C529)

(Synonyms: TYK3, FER) Copy Product Info
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Synonyms: TYK3, FER

Catalog No. TMAT-0867 Copy Product Info
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Anti-FER Monoclonal Antibody (9C529) is a Mouse antibody targeting FER. Anti-FER Monoclonal Antibody (9C529) can be used in WB,IHC,IF.

Anti-FER Monoclonal Antibody
(9C529)

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Product Introduction

Bioactivity
Description
Anti-FER Monoclonal Antibody (9C529) is a Mouse antibody targeting FER. Anti-FER Monoclonal Antibody (9C529) can be used in WB,IHC,IF.
SynonymsTYK3, FER
Ig Type
IgG1
Clone
9C529
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationAscitic fluid containing 0.03% sodium azide.
Concentration1 mg/mL
Research BackgroundFER (fer tyrosine kinase) is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases, which shares a functional domain and is involved in signaling pathways through receptor tyrosine kinases (RTK) and cytokine receptors. The Fes /Fps family is distinct from c-Src, c-Abl and related nRTKs and was originally distinguished as a homolog to retroviral oncoproteins. In vivo, Fer kinase assembles into homotrimers via conserved coiled-coil domains. The N-terminal coiled-coil domains of Fer can autophosphorylate in trans, thereby regulating their cellular function through differential phosphorylation states. Growth factor exposure can induce tyrosine phosphorylation of Fer and recruitment of Fer to RTK complexes containing p85. It is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, and has been shown to be expressed in vascular endothelial cells. Fer is implicated in insulin signaling, cell-cell signaling, human prostatic proliferative diseases, and is involved in the regulation of G1 progression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human FER expressed in E. Coli.
Antigen Species
Human
Gene Name
FER
Gene ID
Protein Name
Tyrosine-protein kinase Fer
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 95 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-FER Monoclonal Antibody (9C529) molecular weight