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Synonyms: SAPK1a, SAPK, PRKM9, p54aSAPK, p54a, JNK-55, JNK2BETA, JNK2B, JNK2ALPHA, JNK2A, JNK2
Anti-MAPK9 Monoclonal Antibody
(4K412)

| Description | Anti-MAPK9 Monoclonal Antibody (4K412) is a Mouse antibody targeting MAPK9. Anti-MAPK9 Monoclonal Antibody (4K412) can be used in WB,FCM. |
| Synonyms | SAPK1a, SAPK, PRKM9, p54aSAPK, p54a, JNK-55, JNK2BETA, JNK2B, JNK2ALPHA, JNK2A, JNK2 |
| Ig Type | IgG1 |
| Clone | 4K412 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MAPK9 (AA: 227-382) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MAPK9 |
| Gene ID | |
| Protein Name | Mitogen-activated protein kinase 9 |
| Uniprot ID |
| Molecular Weight | Theoretical: 48.1 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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