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Anti-LDL Antibody (9N870)

Catalog No. TMAB-08259 Copy Product Info
🥰Excellent
Anti-LDL Antibody (9N870) is a Mouse antibody targeting LDL. Anti-LDL Antibody (9N870) can be used in WB.

Anti-LDL Antibody (9N870)

Copy Product Info
🥰Excellent
Catalog No. TMAB-08259

Anti-LDL Antibody (9N870) is a Mouse antibody targeting LDL. Anti-LDL Antibody (9N870) can be used in WB.

Anti-LDL Antibody
(9N870)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LDL Antibody (9N870) is a Mouse antibody targeting LDL. Anti-LDL Antibody (9N870) can be used in WB.
Ig Type
IgG
Clone
9N870
Reactivity
Human
Verified Activity
100 ng hLDL protein per lane probed with LDL monoclonal antibody respectively, unconjugated (TMAB-08259) at 1:1000 dilution and 4°C overnight incubation. Followed by corresponding conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationSecreted.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundLDL (low-density lipoprotein) is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. LDL enables fats and cholesterol to move within the water based solution of the blood stream. LDL also regulates cholesterol synthesis at these sites. The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells.
Antigen Details
Immunogen
Lipoprotein, low density from human plasma
Antigen Species
Human
Protein Name
human LDL
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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