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Anti-MOG Antibody (9J222)

😃Good
Catalog No. TMAY-00696
Alias NRCLP7, myelin oligodendrocyte glycoprotein, MOGIG2, BTNL11, BTN6

Anti-MOG Antibody (9J222) is a Mouse antibody targeting MOG. Anti-MOG Antibody (9J222) can be used in ELISA.

Anti-MOG Antibody (9J222)

Anti-MOG Antibody (9J222)

😃Good
Catalog No. TMAY-00696Alias NRCLP7, myelin oligodendrocyte glycoprotein, MOGIG2, BTNL11, BTN6
Anti-MOG Antibody (9J222) is a Mouse antibody targeting MOG. Anti-MOG Antibody (9J222) can be used in ELISA.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-MOG Antibody (9J222) is a Mouse antibody targeting MOG. Anti-MOG Antibody (9J222) can be used in ELISA.
AliasNRCLP7, myelin oligodendrocyte glycoprotein, MOGIG2, BTNL11, BTN6
Ig Type
Monoclonal Mouse IgG1
Clone
9J222
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MOG (rh MOG; TMPY-00994; NP_996532.2; Gly30-Tyr149). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundMyelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to the immunoglobulin superfamily and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in the oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce demyelinating multiple sclerosis-like diseases in experimental animals.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human MOG protein (TMPY-00994)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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