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Anti-DYDC2 Antibody (9H835)
😃Good
Catalog No. TMAY-02665
Alias DPY30 domain containing 2
Anti-DYDC2 Antibody (9H835) is a Rabbit antibody targeting DYDC2. Anti-DYDC2 Antibody (9H835) can be used in ICC/IF.
Anti-DYDC2 Antibody (9H835)
Anti-DYDC2 Antibody (9H835)
😃Good
Catalog No. TMAY-02665Alias DPY30 domain containing 2
Anti-DYDC2 Antibody (9H835) is a Rabbit antibody targeting DYDC2. Anti-DYDC2 Antibody (9H835) can be used in ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ICC/IF Reactivity: Human |
| Alias | DPY30 domain containing 2 |
| Ig Type | Rabbit IgG |
| Clone | 9H835 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of Human DYDC2 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human DYDC2 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to nucleus. |
| Application | ICC/IF |
| Recommended Dose | ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human DPY30 domain containing 2 / DYDC2 (rh DPY30 domain containing 2 / DYDC2; TMPY-02957; Q96IM9; Thr102-Pro176). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-30 (Dpy-30) of the worm C. elegans. Dpy-30 is the founding member of a protein family involved in chromatin modifications, notably histone methylation. Mutants affect mating type in yeast and male mating in C. elegans. As part of the MLL1/MLL complex, DPY30 domain containing 2 is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY30 domain containing 2 may also play an indirect or direct role in endosomal transport. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human DPY30 domain containing 2 / DYDC2 Protein (TMPY-02957) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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