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Anti-DYDC2 Antibody (9H835) is a Rabbit antibody targeting DYDC2. Anti-DYDC2 Antibody (9H835) can be used in ICC/IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-DYDC2 Antibody (9H835) is a Rabbit antibody targeting DYDC2. Anti-DYDC2 Antibody (9H835) can be used in ICC/IF. |
Alias | DPY30 domain containing 2 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9H835 |
Reactivity | Human |
Verified Activity | Immunofluorescence staining of Human DYDC2 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human DYDC2 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to nucleus. |
Application | ICC/IF |
Recommended Dose | ICC-IF: 1:20-1:100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human DPY30 domain containing 2 / DYDC2 (rh DPY30 domain containing 2 / DYDC2; TMPY-02957; Q96IM9; Thr102-Pro176). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-30 (Dpy-30) of the worm C. elegans. Dpy-30 is the founding member of a protein family involved in chromatin modifications, notably histone methylation. Mutants affect mating type in yeast and male mating in C. elegans. As part of the MLL1/MLL complex, DPY30 domain containing 2 is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY30 domain containing 2 may also play an indirect or direct role in endosomal transport. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human DPY30 domain containing 2 / DYDC2 Protein (TMPY-02957) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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